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眼睑小汗腺汗孔癌1例罕见病例

A Rare Case of Eccrine Porocarcinoma of the Eyelid.

作者信息

Chua Paul Yihseng, Cornish Kurt Spiteri, Stenhouse Grant, Barras Christopher W

机构信息

a Department of Ophthalmology , Aberdeen University Hospital , Aberdeen , Scotland and.

b Department of Pathology , Raigmore Hospital , Inverness , Scotland.

出版信息

Semin Ophthalmol. 2015;30(5-6):443-5. doi: 10.3109/08820538.2013.874475. Epub 2014 Feb 27.

DOI:10.3109/08820538.2013.874475
PMID:24576261
Abstract

BACKGROUND

To report a rare case of eyelid eccrine porocarcinoma and compare this to previous documented cases in the literature.

MAIN OBSERVATIONS

We report a case of an 86-year-old man who presented with three months' history of irritation in the right eye, who was found to have an irregular nodule on lower eyelid, which was later diagnosed as eccrine porocarcinoma (EPC). The lesion was excised and the defect repaired with Hughes flap. A computerized tomography (CT) scan of the head, neck, and chest showed no metastasis and no lymphadenopathy. There was no evidence of recurrence after 18 months of follow-up.

CONCLUSION

To date, there have been only six cases of eyelid EPC reported in the literature. EPC has significant risk of recurrence and metastases after local excision. It is therefore important to consider it in the differential diagnosis of malignant eyelid tumour. A histological diagnosis should prompt wide margin excision, assessment of the patient for regional lymph node involvement, and imaging for metastatic disease.

摘要

背景

报告1例罕见的眼睑小汗腺汗孔癌病例,并与文献中既往报道的病例进行比较。

主要观察结果

我们报告1例86岁男性患者,有3个月右眼刺激感病史,发现下眼睑有一不规则结节,后来被诊断为小汗腺汗孔癌(EPC)。病变被切除,缺损用休斯皮瓣修复。头部、颈部和胸部的计算机断层扫描(CT)显示无转移且无淋巴结病。随访18个月后无复发迹象。

结论

迄今为止,文献中仅报道了6例眼睑EPC病例。EPC在局部切除后有显著的复发和转移风险。因此,在眼睑恶性肿瘤的鉴别诊断中考虑该病很重要。组织学诊断应促使进行广泛边缘切除、评估患者是否有区域淋巴结受累以及对转移性疾病进行影像学检查。

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Porocarcinoma; presentation and management, a meta-analysis of 453 cases.汗孔癌;临床表现与治疗,453例病例的荟萃分析。
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