Regional difference of inflammatory acne lesions according to β-defensin-2 expression.

作者信息

Choi Dae Kyoung, Li Zheng Jun, Chang In Kyu, Sohn Kyung Cheol, Lee Young, Seo Young Joon, Lee Young Ho, Shi Ge, Kim Chang Deok, Lee Jeung Hoon, Im Myung

机构信息

Department of Dermatology, College of Medicine, Chungnam National University, Daejeon, Korea.

Departments of Anatomy, College of Medicine, Chungnam National University, Daejeon, Korea.

出版信息

J Invest Dermatol. 2014 Jul;134(7):2044-2046. doi: 10.1038/jid.2014.116. Epub 2014 Feb 27.

DOI:10.1038/jid.2014.116

PMID:24577404

Abstract

摘要

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Regional difference of inflammatory acne lesions according to β-defensin-2 expression.

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本文引用的文献

Sebum free fatty acids enhance the innate immune defense of human sebocytes by upregulating beta-defensin-2 expression.皮脂游离脂肪酸通过上调 β-防御素-2 的表达增强人类皮脂腺的固有免疫防御。

J Invest Dermatol. 2010 Apr;130(4):985-94. doi: 10.1038/jid.2009.384. Epub 2009 Dec 24.

Zileuton prevents the activation of the leukotriene pathway and reduces sebaceous lipogenesis.齐留通可抑制白三烯通路的激活并减少皮脂生成。

Exp Dermatol. 2010 Feb;19(2):148-50. doi: 10.1111/j.1600-0625.2009.00929.x. Epub 2009 Jul 23.

Histone H4 is a major component of the antimicrobial action of human sebocytes.组蛋白H4是人类皮脂腺细胞抗菌作用的主要成分。

J Invest Dermatol. 2009 Oct;129(10):2489-96. doi: 10.1038/jid.2009.106. Epub 2009 Jun 18.

Sebocytes express functional cathelicidin antimicrobial peptides and can act to kill propionibacterium acnes.皮脂细胞表达功能性的抗菌肽，并可起到杀灭痤疮丙酸杆菌的作用。

J Invest Dermatol. 2008 Jul;128(7):1863-6. doi: 10.1038/sj.jid.5701235. Epub 2008 Jan 17.

Does facial sebum excretion really affect the development of acne?面部皮脂分泌真的会影响痤疮的发展吗？

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A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria.一种 toll 样受体 2 反应性脂质效应途径可保护哺乳动物免受革兰氏阳性菌引起的皮肤感染。

Infect Immun. 2005 Aug;73(8):4512-21. doi: 10.1128/IAI.73.8.4512-4521.2005.

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J Invest Dermatol. 2001 Nov;117(5):1120-5. doi: 10.1046/j.0022-202x.2001.01569.x.

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