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Sebocytes express functional cathelicidin antimicrobial peptides and can act to kill propionibacterium acnes.

作者信息

Lee Dong-Youn, Yamasaki Kenshi, Rudsil Jennifer, Zouboulis Christos C, Park Geon Tae, Yang Jun-Mo, Gallo Richard L

出版信息

J Invest Dermatol. 2008 Jul;128(7):1863-6. doi: 10.1038/sj.jid.5701235. Epub 2008 Jan 17.

DOI:10.1038/sj.jid.5701235
PMID:18200058
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2632971/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0181/2632971/e2ed311023f2/nihms88599f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0181/2632971/906c5f0b86ea/nihms88599f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0181/2632971/e2ed311023f2/nihms88599f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0181/2632971/906c5f0b86ea/nihms88599f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0181/2632971/e2ed311023f2/nihms88599f2.jpg

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Nat Med. 2007 Aug;13(8):975-80. doi: 10.1038/nm1616. Epub 2007 Aug 5.
2
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Microbes Infect. 2006 Jul;8(8):2195-205. doi: 10.1016/j.micinf.2006.04.001. Epub 2006 May 19.
3
A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria.
皮脂腺：维持体内平衡与炎症性皮肤病平衡的关键因素。
Cells. 2025 May 20;14(10):747. doi: 10.3390/cells14100747.
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JID Innov. 2025 Feb 5;5(3):100354. doi: 10.1016/j.xjidi.2025.100354. eCollection 2025 May.
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Revealing the Transcriptional and Metabolic Characteristics of Sebocytes Based on the Donkey Cell Transcriptome Atlas.基于驴细胞转录组图谱揭示皮脂腺细胞的转录和代谢特征。
Adv Sci (Weinh). 2025 Apr;12(16):e2413819. doi: 10.1002/advs.202413819. Epub 2025 Feb 27.
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Significance of host antimicrobial peptides in the pathogenesis and treatment of acne vulgaris.宿主抗菌肽在寻常痤疮发病机制及治疗中的意义
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