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增强尿液分析在孕期无症状菌尿检测中的应用

Enhanced urinalysis in the detection of asymptomatic bacteriuria in pregnancy.

作者信息

Aigere E O S, Okusanya B O, Eigbefoh J O, Okome G B O

机构信息

Department of Obstetrics and Gynaecology, Federal Medical Centre Katsina.

Department of Obstetrics and Gynaecology, College of Medicine, University of Lagos.

出版信息

Nig Q J Hosp Med. 2013 Apr-Jun;23(2):105-9.

Abstract

BACKGROUND

Detection and treatment of asymptomatic bacteriuria (ASB) in pregnancy is important to avert the attendant maternal and fetal morbidity. Other than urine culture, no other screening test is unequivocal.

OBJECTIVE

The use of enhanced urinalysis test to detect ASB in pregnancy was investigated.

METHODS

This was a prospective observational study which compared enhanced urinalysis with dipstick tests and urine culture. Clean catch midstream urine specimen was collected from 150 consecutive asymptomatic pregnant women. Tests of validity were used for comparison.

RESULTS

Enhanced urinalysis detected bacteriuria as much as urine culture (4% vs. 4.7%). Itwas 57.1% sensitive and 98.6% specific. It had a false negative rate of 42.9% and was 96.7% accurate when compared to urine culture. Enhanced urinalysis took 1-2 hours to be done and required skills to use the microscope and was more expensive than dipstick urinalysis.

CONCLUSION

The accuracy of enhanced urinalysis and its ability to detect ASB as much as urine culture connotes that it can be used to detect asymptomatic bacteriuria in pregnancy albeit only in secondary and tertiary health centres because of the cost and technicality involved.

摘要

背景

孕期无症状菌尿(ASB)的检测与治疗对于避免随之而来的母婴发病情况至关重要。除了尿培养外,没有其他筛查测试是明确无误的。

目的

研究使用强化尿液分析检测孕期无症状菌尿。

方法

这是一项前瞻性观察性研究,将强化尿液分析与试纸条测试及尿培养进行比较。从150名连续的无症状孕妇中收集清洁中段尿标本。使用有效性测试进行比较。

结果

强化尿液分析检测菌尿的能力与尿培养相当(4%对4.7%)。其敏感性为57.1%,特异性为98.6%。与尿培养相比,其假阴性率为42.9%,准确率为96.7%。强化尿液分析需要1至2小时完成,使用显微镜需要一定技巧,且比试纸条尿液分析费用更高。

结论

强化尿液分析的准确性及其检测无症状菌尿的能力与尿培养相当,这意味着它可用于检测孕期无症状菌尿,不过由于成本和技术问题,仅适用于二级和三级医疗中心。

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