Holmes G E, Hassanein R S
University of Kansas School of Medicine, Kansas City.
Am Fam Physician. 1988 Sep;38(3):185-9.
Minor abnormalities reflect problems in prenatal development and can provide useful clues to the presence of major anomalies or developmental problems. In a comparative study, children with Down's syndrome, as expected, had significantly more minor abnormalities than those with other syndromes or major anomalies and those with developmental delay and/or cerebral palsy of unknown etiology. These two groups were not significantly different from each other in the number of minor abnormalities, but both had significantly more abnormalities than the group of normal children.
轻微异常反映了产前发育中的问题，并且可以为重大畸形或发育问题的存在提供有用线索。在一项比较研究中，正如预期的那样，唐氏综合征患儿的轻微异常明显多于患有其他综合征或重大畸形的患儿，以及患有病因不明的发育迟缓或脑瘫的患儿。这两组患儿在轻微异常的数量上没有显著差异，但两者的异常都明显多于正常儿童组。
