Centro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso, Avda. Gran Bretaña 1111, 2360102, Valparaíso, Chile.
J Fish Biol. 2013 Nov;83(5):1468-73. doi: 10.1111/jfb.12253.
This study compared the contribution of the Ca²⁺-activated Cl⁻ conductance to the electroolfactogram (EOG) evoked by different odorant classes between the marine Cabinza grunt Isacia conceptionis and rainbow trout Oncorhynchus mykiss. The Ca²⁺-activated Cl⁻ channel blocker niflumic acid significantly diminished odorant responses in O. mykiss, but had no effect on the EOG in I. conceptionis, supporting the notion that Ca²⁺-activated Cl⁻ channels may not operate as odorant transduction current amplifiers in this marine teleost.
本研究比较了 Ca²⁺-激活的 Cl⁻电导在 Marine Cabinza grunt Isacia conceptionis 和 Rainbow trout Oncorhynchus mykiss 对不同气味类别诱发的电嗅图（EOG）中的贡献。Ca²⁺-激活的 Cl⁻通道阻滞剂尼氟灭酸显著降低了 O. mykiss 对气味的反应，但对 I. conceptionis 的 EOG 没有影响，这支持了 Ca²⁺-激活的 Cl⁻通道在这种海洋硬骨鱼中可能不作为气味转导电流放大器的观点。
