Veldhoen Simon, Laqmani Azien, Derlin Thorsten, Karul Murat, Hammerle Diego, Buhk Jan-Hendrik, Sehner Susanne, Nagel Hans D, Chun Felix, Adam Gerhard, Regier Marc
Department of Diagnostic and Interventional Radiology, University Medical Center Würzburg, Würzburg, Germany.
J Med Imaging Radiat Oncol. 2014;58(3):283-90. doi: 10.1111/1754-9485.12159. Epub 2014 Mar 3.
Multidetector CT (MDCT) is the established imaging modality in diagnostics of urolithiasis. The aim of iterative reconstruction (IR) is to allow for a radiation dose reduction while maintaining high image quality. This study evaluates its performance in MDCT for assessment of urolithiasis.
Fifty-two patients underwent non-contrast abdominal MDCT. Twenty-six patients were referred to MDCT under suspicion of urolithiasis, and examined using a dose-reduced scan protocol (RDCT). Twenty-six patients, who had undergone standard-dose MDCT, served as reference for radiation dose comparison. RDCT images were reconstructed using an IR system (iDose4™, Philips Healthcare, Cleveland, OH, USA). Objective image noise (OIN) was recorded and five radiologists rated the subjective image quality independently. Radiation parameters were derived from the scan protocols.
The CTDIvol could be reduced by 50% to 5.8 mGy (P < 0.0001). The same reduction was achieved for DLP and effective dose to 253 ± 27 mGy*cm (P < 0.0001) and 3.9 ± 0.4 mSv (P < 0.0001). IR led to a reduction of the OIN of up to 61% compared with classic filtered back projection (FBP) (P < 0.0001). The OIN declined with increasing IR levels. RDCT with FBP showed the lowest scores of subjective image quality (2.32 ± 0.04). Mean scores improved with increasing IR levels. iDose6 was rated with the best mean score (3.66 ± 0.04).
The evaluated IR-tool and protocol may be applied to achieve a considerable radiation dose reduction in MDCT for diagnostics of urolithiasis while maintaining a confident image quality. Best image quality, suitable for evaluation of the entire abdomen concerning differential diagnoses, was achieved with iDose6.
多排螺旋CT(MDCT)是尿路结石诊断中既定的成像方式。迭代重建(IR)的目的是在保持高图像质量的同时降低辐射剂量。本研究评估其在MDCT评估尿路结石中的性能。
52例患者接受了非增强腹部MDCT检查。26例因怀疑尿路结石而接受MDCT检查的患者,采用低剂量扫描方案(RDCT)进行检查。26例接受标准剂量MDCT检查的患者作为辐射剂量比较的对照。RDCT图像使用IR系统(iDose4™,飞利浦医疗保健公司,美国俄亥俄州克利夫兰)进行重建。记录客观图像噪声(OIN),5名放射科医生独立对主观图像质量进行评分。辐射参数来自扫描方案。
容积CT剂量指数(CTDIvol)可降低50%至5.8 mGy(P < 0.0001)。剂量长度乘积(DLP)和有效剂量也有相同程度的降低,分别降至253±27 mGy·cm(P < 0.0001)和3.9±0.4 mSv(P < 0.0001)。与传统滤波反投影(FBP)相比,IR使OIN降低了高达61%(P < 0.0001)。OIN随IR水平的增加而下降。采用FBP的RDCT主观图像质量得分最低(2.32±0.04)。平均得分随IR水平的增加而提高。iDose6的平均得分最高(3.66±0.04)。
所评估的IR工具和方案可用于在MDCT诊断尿路结石时大幅降低辐射剂量,同时保持可靠的图像质量。使用iDose6可获得适合评估整个腹部鉴别诊断的最佳图像质量。