非恶性疾病中的肿瘤标志物。
Tumor markers in non-malignant diseases.
作者信息
Touitou Y, Bogdan A
机构信息
Department of Biochemistry, Faculté de Médecine, Pitié-Salpêtrière, Paris, France.
出版信息
Eur J Cancer Clin Oncol. 1988 Jul;24(7):1083-91. doi: 10.1016/0277-5379(88)90113-7.
This paper reviews the specificity of tumor markers recently introduced in clinical use, namely CA 19-9, CA 125, CA 15-3, CA 50 and SCC antigen. It appears that a large number of either biological conditions (age, sex, pregnancy, menstruation etc.), intoxication (smoking and alcohol addictions) or various non-malignant diseases do affect the serum levels of tumor markers. These data are of practical use in the interpretation of tumor marker determinations in the follow-up of cancer patients.
本文综述了近期临床应用中引入的肿瘤标志物的特异性，即CA 19-9、CA 125、CA 15-3、CA 50和鳞状细胞癌抗原。似乎大量的生物学状况（年龄、性别、妊娠、月经等）、中毒（吸烟和酗酒）或各种非恶性疾病都会影响肿瘤标志物的血清水平。这些数据在癌症患者随访中肿瘤标志物测定结果的解释方面具有实际应用价值。
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