Johnston J D, Liao L, Dolovich A T, Leswick D A, Kontulainen S A
Department of Mechanical Engineering, College of Engineering.
J Musculoskelet Neuronal Interact. 2014 Mar;14(1):104-10.
To determine the in vivo precision of MRI-based measures of bone and muscle traits at the hip.
Left proximal femoral neck and shaft of 14 participants (5M:9 F; age:21-68) were scanned 3 times using a 1.5 T MRI. Commercial and custom image processing methods were used to derive bone geometry and strength traits at the proximal femoral neck and shaft along with muscle area of various muscle groups at the shaft site. For precision, root mean square coefficients of variation (CV%rms) and standard deviations (SDrms) were calculated.
At the femoral neck, CV%rms for area-based bone measures ranged between 1.7-5.0%; CV%rms for cortical thickness varied from 4.7 to 5.6%; and CV%rms for bending, torsional and buckling-based strength indices ranged between 4.6-7.1%. At the femoral shaft, CV%rms for bone area ranged between 1.2-3.0%; CV%rms for cortical thickness varied from 1.7 to 2.0%; and CV%rms for bending and buckling-based strength indices ranged between 1.4-3.1%. For muscle area, CV%rms ranged between 1.3-4.5%.
MRI-based measures of bone and muscle traits at the proximal femoral neck and shaft demonstrated in vivo precision errors <7.1%. MRI is a promising 3D technique for monitoring changes in bone and muscle at the clinically important hip.
确定基于MRI测量髋部骨骼和肌肉特征的体内精度。
对14名参与者（5名男性：9名女性；年龄：21 - 68岁）的左股骨近端颈和骨干进行1.5T MRI扫描，共扫描3次。使用商业和定制图像处理方法得出股骨近端颈和骨干的骨几何形状和强度特征，以及骨干部位各肌肉群的肌肉面积。为评估精度，计算均方根变异系数（CV%rms）和标准差（SDrms）。
在股骨颈处，基于面积的骨测量指标的CV%rms在1.7 - 5.0%之间；皮质厚度的CV%rms在4.7%至5.6%之间；基于弯曲、扭转和屈曲的强度指数的CV%rms在4.6 - 7.1%之间。在股骨干处，骨面积的CV%rms在1.2 - 3.0%之间；皮质厚度的CV%rms在1.7%至2.0%之间；基于弯曲和屈曲的强度指数的CV%rms在1.4 - 3.1%之间。对于肌肉面积，CV%rms在1.
