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肝活检后复发性胃肠道出血和肝梗死

Recurrent gastrointestinal bleeding and hepatic infarction after liver biopsy.

作者信息

Bishehsari Faraz, Ting Peng-Sheng, Green Richard M

机构信息

Faraz Bishehsari, Richard M Green, Division of Gastroenterology and Hepatology, Feinberg School of Medicine, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611, United States.

出版信息

World J Gastroenterol. 2014 Feb 21;20(7):1878-81. doi: 10.3748/wjg.v20.i7.1878.

Abstract

Hepatic artery pseudoaneurysms (HAP) are rare events, particularly after liver biopsy, but can be associated with serious complications. Therefore a high suspicion is necessary for timely diagnosis and appropriate treatment. We report on a case of HAP that potentially formed after a liver biopsy in a patient with sarcoidosis. The HAP in our case was virtually undetectable initially by angiography but resulted in several complications including recurrent gastrointestinal bleeding, hemorrhagic cholecystitis and finally hepatic infarction with abscess formation until it became detectable at a size of 5-mm. The patient remains asymptomatic over a year after endovascular embolization of the HAP. In this report, we demonstrate that a small HAP can avoid detection by angiography at an early stage while being symptomatic for a prolonged course. A high clinical suspicion with a close clinical/radiological follow-up is needed in symptomatic patients with history of liver biopsy despite initial negative work up. Once diagnosed, HAP can be safely and effectively treated by endovascular embolization.

摘要

肝动脉假性动脉瘤(HAP)较为罕见,尤其是在肝活检后,但可能伴有严重并发症。因此,高度怀疑对于及时诊断和恰当治疗至关重要。我们报告一例结节病患者在肝活检后可能形成的HAP病例。我们病例中的HAP最初通过血管造影几乎无法检测到,但引发了多种并发症,包括反复胃肠道出血、出血性胆囊炎,最终导致肝梗死并形成脓肿,直到其直径达5毫米时才被检测到。在对该HAP进行血管内栓塞治疗一年多后,患者仍无症状。在本报告中,我们证明了小的HAP在早期可通过血管造影避免被检测到,同时在较长病程中出现症状。对于有肝活检史且有症状的患者,尽管初始检查结果为阴性,但仍需高度临床怀疑并进行密切的临床/放射学随访。一旦确诊,HAP可通过血管内栓塞安全有效地治疗。

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