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[临床医学中的跨上皮电势差(tPD)。测量胃肠道电势差的方法学方面]

[Transepithelial electric potential difference (tPD) in clinical medicine. Methodologic aspects of measuring potential differences in the gastrointestinal tract].

作者信息

König A, Jährig K, Ballke E H, Nikolaides N, Stenger R

机构信息

Klinik für Kindermedizin des Bereichs Medizin, Ernst-Moritz-Arndt-Universität, Greifswald.

出版信息

Dtsch Z Verdau Stoffwechselkr. 1988;48(2):65-74.

PMID:2458905
Abstract

The transepithelial potential difference of the gastrointestinal mucosa as a diagnostic parameter obtains increasing importance in clinical medicine. Therefore it is necessary to consider methodical aspects of the tPD-measurement under in-vivo conditions. The current paper presents methodical considerations for instance electrode arrangement, positions, composition of the electrolyte electrodes, diffusion potentials, rate of perfusion and unstirred water layer and their influence on the tPD-measurement.

摘要

胃肠道黏膜的跨上皮电位差作为一种诊断参数在临床医学中日益重要。因此,有必要考虑体内条件下跨上皮电位差测量的方法学方面。本文介绍了一些方法学方面的考虑因素,例如电极布置、位置、电解质电极的组成、扩散电位、灌注速率和未搅动水层及其对跨上皮电位差测量的影响。

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Dtsch Z Verdau Stoffwechselkr. 1988;48(2):65-74.
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