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使用OpenLab框架进行高效样本跟踪。

Efficient sample tracking with OpenLabFramework.

作者信息

List Markus, Schmidt Steffen, Trojnar Jakub, Thomas Jochen, Thomassen Mads, Kruse Torben A, Tan Qihua, Baumbach Jan, Mollenhauer Jan

机构信息

1] Lundbeckfonden Center of Excellence in Nanomedicine NanoCAN, University of Southern Denmark, Odense, DK [2] Institute of Molecular Medicin (IMM), University of Southern Denmark, Odense, DK [3] Clinical Institute (CI), University of Southern Denmark, Odense, DK.

1] Lundbeckfonden Center of Excellence in Nanomedicine NanoCAN, University of Southern Denmark, Odense, DK [2] Institute of Molecular Medicin (IMM), University of Southern Denmark, Odense, DK.

出版信息

Sci Rep. 2014 Mar 4;4:4278. doi: 10.1038/srep04278.

Abstract

The advance of new technologies in biomedical research has led to a dramatic growth in experimental throughput. Projects therefore steadily grow in size and involve a larger number of researchers. Spreadsheets traditionally used are thus no longer suitable for keeping track of the vast amounts of samples created and need to be replaced with state-of-the-art laboratory information management systems. Such systems have been developed in large numbers, but they are often limited to specific research domains and types of data. One domain so far neglected is the management of libraries of vector clones and genetically engineered cell lines. OpenLabFramework is a newly developed web-application for sample tracking, particularly laid out to fill this gap, but with an open architecture allowing it to be extended for other biological materials and functional data. Its sample tracking mechanism is fully customizable and aids productivity further through support for mobile devices and barcoded labels.

摘要

生物医学研究中新技术的进步导致实验通量急剧增长。因此,项目规模稳步扩大,涉及的研究人员数量也更多。传统使用的电子表格已不再适用于跟踪大量生成的样本,需要被先进的实验室信息管理系统所取代。这类系统已经大量开发,但它们往往局限于特定的研究领域和数据类型。到目前为止,一个被忽视的领域是载体克隆文库和基因工程细胞系的管理。OpenLabFramework是一个新开发的用于样本跟踪的网络应用程序,特别设计用于填补这一空白,但其开放的架构允许它扩展到其他生物材料和功能数据。其样本跟踪机制完全可定制,并通过对移动设备和条形码标签的支持进一步提高了工作效率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f192/3940979/c9431ece6945/srep04278-f1.jpg

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