Department of Breeding and Genetic Resources, Institute of Farm Animal Genetics, Neustadt, Germany.
BMC Bioinformatics. 2011 Oct 31;12:425. doi: 10.1186/1471-2105-12-425.
Long-term sample storage, tracing of data flow and data export for subsequent analyses are of great importance in genetics studies. Therefore, molecular labs do need a proper information system to handle an increasing amount of data from different projects.
We have developed a molecular labs information management system (MolabIS). It was implemented as a web-based system allowing the users to capture original data at each step of their workflow. MolabIS provides essential functionality for managing information on individuals, tracking samples and storage locations, capturing raw files, importing final data from external files, searching results, accessing and modifying data. Further important features are options to generate ready-to-print reports and convert sequence and microsatellite data into various data formats, which can be used as input files in subsequent analyses. Moreover, MolabIS also provides a tool for data migration.
MolabIS is designed for small-to-medium sized labs conducting Sanger sequencing and microsatellite genotyping to store and efficiently handle a relative large amount of data. MolabIS not only helps to avoid time consuming tasks but also ensures the availability of data for further analyses. The software is packaged as a virtual appliance which can run on different platforms (e.g. Linux, Windows). MolabIS can be distributed to a wide range of molecular genetics labs since it was developed according to a general data model. Released under GPL, MolabIS is freely available at http://www.molabis.org.
在遗传学研究中，长期的样本存储、数据流程的跟踪以及后续分析的数据导出都非常重要。因此，分子实验室确实需要一个适当的信息系统来处理来自不同项目的大量数据。
我们开发了一个分子实验室信息管理系统（MolabIS）。它被实现为一个基于网络的系统，允许用户在其工作流程的每个步骤捕获原始数据。MolabIS 提供了管理个人信息、跟踪样本和存储位置、捕获原始文件、从外部文件导入最终数据、搜索结果、访问和修改数据的基本功能。进一步重要的功能是生成准备打印的报告的选项，以及将序列和微卫星数据转换为各种数据格式的选项，这些数据格式可以用作后续分析的输入文件。此外，MolabIS 还提供了数据迁移工具。
MolabIS 专为进行 Sanger 测序和微卫星基因分型的中小规模实验室设计，用于存储和高效处理相对大量的数据。MolabIS 不仅有助于避免耗时的任务，还确保了数据可用于进一步分析。该软件被打包为一个虚拟机，可以在不同的平台（如 Linux、Windows）上运行。MolabIS 可以分发给广泛的分子遗传学实验室，因为它是根据通用数据模型开发的。根据 GPL 发布，MolabIS 可在 http://www.molabis.org 免费获得。
