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子宫内膜活检中异常子宫出血的组织病理学模式。

Histopathological pattern of abnormal uterine bleeding in endometrial biopsies.

作者信息

Vaidya S, Lakhey M, Vaidya S, Sharma P K, Hirachand S, Lama S, KC S

机构信息

Department of Pathology, Kathmandu Medical College, Sinamangal, Kathmandu, Nepal.

Department of Obstertrics and Gynaecology, Maternity Hospital, Thapathali, Kathmandu, Nepal.

出版信息

Nepal Med Coll J. 2013 Mar;15(1):74-7.

Abstract

Abnormal uterine bleeding is a common presenting complaint in gyanecology out patient department. Histopathological evaluation of the endometrial samples plays a significant role in the diagnosis of abnormal uterine bleeding. This study was carried out to determine the histopathological pattern of the endometrium in women of various age groups presenting with abnormal uterine bleeding. Endometrial biopsies and curettings of patients presenting with abnormal uterine bleeding was retrospectively studied. A total of 403 endometrial biopsies and curettings were analyzed. The age of the patients ranged from 18 to 70 years. Normal cyclical endometrium was seen in 165 (40.94%) cases, followed by 54 (13.40%) cases of disordered proliferative endometrium and 44 (10.92%) cases of hyperplasia. Malignancy was seen in 10 (2.48%) cases. Hyperplasia and malignancy were more common in the perimenopausal and postmenopausal age groups. Histopathological examination of endometrial biopsies and curettings in patients presenting with abnormal uterine bleeding showed a wide spectrum of changes ranging from normal endometrium to malignancy. Endometrial evaluation is specially recommended in women of perimenopausal and postmenopausal age groups presenting with AUB, to rule out a possibility of any preneoplastic condition or malignancy.

摘要

异常子宫出血是妇科门诊常见的就诊主诉。子宫内膜样本的组织病理学评估在异常子宫出血的诊断中起着重要作用。本研究旨在确定出现异常子宫出血的不同年龄组女性子宫内膜的组织病理学模式。对出现异常子宫出血患者的子宫内膜活检和刮宫样本进行回顾性研究。共分析了403份子宫内膜活检和刮宫样本。患者年龄范围为18至70岁。165例(40.94%)可见正常周期性子宫内膜,其次是54例(13.40%)无序增殖性子宫内膜和44例(10.92%)增生。10例(2.48%)发现恶性病变。增生和恶性病变在围绝经期和绝经后年龄组中更为常见。对出现异常子宫出血患者的子宫内膜活检和刮宫样本进行组织病理学检查显示,从正常子宫内膜到恶性病变有广泛的变化。特别建议对出现AUB的围绝经期和绝经后年龄组女性进行子宫内膜评估,以排除任何癌前病变或恶性肿瘤的可能性。

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