Department of Obstetrics and Gynecology, Lumbini Medical College and Teaching Hospital, Palpa, Nepal.
Department of Pathology, Lumbini Medical College and Teaching Hospital, Palpa, Nepal.
JNMA J Nepal Med Assoc. 2022 Feb 15;60(246):121-125. doi: 10.31729/jnma.6954.
Abnormal uterine bleeding accounts for more than 70% of complaints in peri- and post-menopausal women. The main purpose of investigating them is to rule out premalignant and malignant endometrial lesions. This study aimed to find out the prevalence of abnormal uterine bleeding among out-patients visiting the gynecology department of a tertiary care hospital.
This descriptive cross-sectional study was conducted in the Department of Obstetrics and Gynecology of a tertiary care center from August 1, 2020 to April 23, 2021. Ethical approval was obtained from the Institutional Review Committee of the same institution (IRC-LMC 07-C/020). A total of 2680 women visiting gynecology outpatient departments were included by convenience sampling technique. Women with abnormal uterine bleeding were evaluated by endometrial thickness measurement and endometrial biopsies. Statistical Package for the Social Sciences version 16 was used for data analysis. Point estimate at 95% Confidence Interval was calculated along with frequency, percentage, mean and standard deviation.
Among 2680 women visiting the gynecology outpatient department, the prevalence of abnormal uterine bleeding was 240 (8.9%) (7.82-9.98 at 95% Confidence Interval). The mean endometrial thickness was 10.15±6.63mm. Majority of patients 104 (43.3%) had endometrial thickness >10mm. Sixty-six (27.8%) patients had disordered proliferative endometrium while endometrial carcinoma was noted in three (1.2%) patients. Atrophic endometrium was observed in 17 (7.2%) and endometrial hyperplasia in nine (3.8%) patients.
The prevalence of abnormal uterine bleeding was found to be higher in comparison to other studies. Disordered proliferative endometrium was the most common histopathological finding followed by secretory phase endometrium.
异常子宫出血占绝经前后妇女就诊主诉的 70%以上。对其进行检查的主要目的是排除子宫内膜的癌前病变和恶性病变。本研究旨在了解三级保健医院妇科门诊就诊患者异常子宫出血的患病率。
这是一项在 2020 年 8 月 1 日至 2021 年 4 月 23 日期间在一家三级保健中心的妇产科进行的描述性横断面研究。该研究获得了同一机构伦理审查委员会(IRC-LMC 07-C/020)的批准。采用便利抽样技术,共纳入 2680 名就诊于妇科门诊的女性。对异常子宫出血的女性通过子宫内膜厚度测量和子宫内膜活检进行评估。采用社会科学统计软件包 16 版进行数据分析。计算了 95%置信区间的点估计值以及频率、百分比、平均值和标准差。
在 2680 名就诊于妇科门诊的女性中,异常子宫出血的患病率为 240 例(8.9%)(95%置信区间为 7.82-9.98)。平均子宫内膜厚度为 10.15±6.63mm。大多数患者 104 例(43.3%)的子宫内膜厚度>10mm。66 例(27.8%)患者存在增生期子宫内膜紊乱,3 例(1.2%)患者存在子宫内膜癌。17 例(7.2%)为萎缩性子宫内膜,9 例(3.8%)为子宫内膜增生。
与其他研究相比,本研究发现异常子宫出血的患病率较高。增生期子宫内膜紊乱是最常见的组织病理学发现,其次是分泌期子宫内膜。