de Keyser K, Janssens S, Buys N
Livestock Genetics, Department of Biosystems, KU Leuven, Heverlee (Leuven), Belgium.
Equine Vet J. 2015 May;47(3):260-6. doi: 10.1111/evj.12256. Epub 2014 Apr 20.
The objective of this review was to summarise and evaluate the current state of knowledge about chronic progressive lymphoedema in draught horses. Clinical signs of this multifactorial disorder are mainly restricted to the lower limbs, comprising progressively deteriorating skin, swelling and deformation. Although typical lesions were first reported at the beginning of the 20th century, chronic progressive lymphoedema was recognised as a specific syndrome only in 2003, and since then research has driven forward. Despite the high prevalence in some breeds and the serious economic impact, the pathogenesis is not fully understood, and the available treatment options remain symptomatic and noncurative. There is a need to improve diagnostic techniques and to develop selection tools.
本综述的目的是总结和评估有关役用马慢性进行性淋巴水肿的当前知识状况。这种多因素疾病的临床症状主要局限于下肢，包括皮肤逐渐恶化、肿胀和变形。尽管典型病变在20世纪初首次被报道，但慢性进行性淋巴水肿直到2003年才被确认为一种特定综合征，从那时起研究不断推进。尽管在一些品种中患病率很高且具有严重的经济影响，但其发病机制尚未完全了解，现有的治疗选择仍然只是对症治疗且无法治愈。需要改进诊断技术并开发选择工具。
