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[肉瘤切除术后的长期功能结果]

[Long-term functional results after sarcoma resection].

作者信息

Steinau H-U, Hauser J, Farzaliyev F, Podleska L

机构信息

Klinik für Unfallchirurgie/Plastische Chirurgie, Sarkomzentrum am Westdeutschen Tumorzentrum CCC, Universitätsklinikum Essen, Universität Duisburg-Essen, Hufeland Str. 55, 45147, Essen, Deutschland,

出版信息

Chirurg. 2014 Mar;85(3):215-20, 222-3. doi: 10.1007/s00104-013-2603-z.

DOI:10.1007/s00104-013-2603-z
PMID:24595478
Abstract

Multimodal treatment of malignant tumors of the musculoskeletal system with R0 in sano resection plays a key role in prevention of local recurrence in soft tissue and bone sarcoma. In cases of unavoidable neuromuscular or osseous defects, current plastic and orthoplastic reconstruction techniques avoid limb amputation in the majority of patients. Clinical long-term results demonstrate that large resection defects do not necessarily result in impaired limb function if multidisciplinary procedures are integrated. In oncologically necessary major limb amputation, segmental resection and replantation of distal limb parts should be considered which provide end-bearing long stump formation. The functional conditions of long-term surviving elderly patients should be integrated into surgical decision-making and rehabilitation efforts.

摘要

在肌肉骨骼系统恶性肿瘤的多模式治疗中,进行R0根治性切除对预防软组织和骨肉瘤的局部复发起着关键作用。在不可避免地出现神经肌肉或骨缺损的情况下,目前的整形和正颌整形重建技术可使大多数患者避免截肢。临床长期结果表明,如果采用多学科手术,大面积切除缺损不一定会导致肢体功能受损。在肿瘤学上必要的大肢体截肢手术中,应考虑进行节段性切除和远端肢体部分的再植,以形成有承重能力的长残端。长期存活老年患者的功能状况应纳入手术决策和康复工作中。

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1
[Long-term functional results after sarcoma resection].[肉瘤切除术后的长期功能结果]
Chirurg. 2014 Mar;85(3):215-20, 222-3. doi: 10.1007/s00104-013-2603-z.
2
[Amputation or limb salvage? Assessing quality of life after tumor operations of the lower extremity].截肢还是保肢?评估下肢肿瘤手术后的生活质量
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J Egypt Natl Canc Inst. 2008 Jun;20(2):196-207.
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[Sarcoma of the hand and wrist].[手部和腕部肉瘤]
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Compartmental resection for subfascial extremity soft tissue sarcoma and quality of life in long-term survivors.筋膜下肢体软组织肉瘤的分区切除术与长期生存者的生活质量。
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本文引用的文献

1
The vascularized fibular graft in the pediatric upper extremity: a durable, biological solution to large oncologic defects.小儿上肢带血管蒂腓骨移植:一种针对大型肿瘤性缺损的持久生物解决方案。
Sarcoma. 2013;2013:321201. doi: 10.1155/2013/321201. Epub 2013 Oct 7.
2
Sociooccupational and physical outcomes more than 20 years after the diagnosis of osteosarcoma in children and adolescents: limb salvage versus amputation.儿童和青少年骨肉瘤诊断后 20 多年的社会职业和身体结果:保肢与截肢。
Cancer. 2013 Oct 15;119(20):3727-36. doi: 10.1002/cncr.28277. Epub 2013 Jul 31.
3
Surgical margins and handling of soft-tissue sarcoma in extremities: a clinical practice guideline.
四肢软组织肉瘤的手术切缘和处理:临床实践指南。
Curr Oncol. 2013 Jun;20(3):e247-54. doi: 10.3747/co.20.1308.
4
A systematic review of the recent quality of life studies in adult extremity sarcoma survivors.对成年肢体肉瘤幸存者近期生活质量研究的系统评价。
Sarcoma. 2012;2012:171342. doi: 10.1155/2012/171342. Epub 2012 Aug 23.
5
Does limb-salvage surgery offer patients better quality of life and functional capacity than amputation?保肢手术是否比截肢能为患者提供更好的生活质量和功能能力?
Clin Orthop Relat Res. 2012 Jul;470(7):2000-6. doi: 10.1007/s11999-012-2271-1.
6
Similar survival but better function for patients after limb salvage versus amputation for distal tibia osteosarcoma.保肢治疗与截肢治疗对胫骨远端骨肉瘤患者的生存情况相似,但保肢治疗可改善患者的功能。
Clin Orthop Relat Res. 2012 Jun;470(6):1735-48. doi: 10.1007/s11999-011-2238-7. Epub 2012 Jan 24.
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[Surgical margins in soft tissue sarcoma of the extremities].[肢体软组织肉瘤的手术切缘]
Pathologe. 2011 Feb;32(1):57-64. doi: 10.1007/s00292-010-1394-y.
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Limb salvage in malignant tumors.肢体恶性肿瘤保肢治疗。
Semin Plast Surg. 2010 Feb;24(1):18-33. doi: 10.1055/s-0030-1253240.
9
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10
Lymphedema beyond breast cancer: a systematic review and meta-analysis of cancer-related secondary lymphedema.非乳腺癌相关淋巴水肿:癌症相关继发性淋巴水肿的系统评价和荟萃分析。
Cancer. 2010 Nov 15;116(22):5138-49. doi: 10.1002/cncr.25458.