Department of Neuro-Oncology, University of Texas MD Anderson Cancer Center, P.O. Box 301402, Unit #431, Houston, TX, 77232-1402, USA,
Curr Oncol Rep. 2014 May;16(5):383. doi: 10.1007/s11912-014-0383-3.
Posterior reversible encephalopathy syndrome is a well-recognized entity associated with a variety of benign and malignant conditions. This syndrome typically manifests itself with headache, visual loss, and seizures. Radiographic abnormalities consist of white matter edema involving the posterior parietal and occipital lobes, manifested as increased T2 and fluid-attenuated inversion recovery signal intensity on magnetic resonance imaging. In the last decade, there has been a reported increase in the incidence of posterior reversible encephalopathy syndrome in cancer patients. The diagnosis can be challenging in this patient population. Early recognition and initiation of appropriate therapy with removal of the causative agent is essential in order to prevent permanent neurologic sequelae.
后部可逆性脑病综合征是一种与多种良性和恶性疾病相关的已被充分认识的病症。该综合征通常表现为头痛、视力丧失和癫痫发作。影像学异常包括累及顶枕叶后部的脑白质水肿，磁共振成像上表现为 T2 加权像和液体衰减反转恢复信号强度增加。在过去十年中，癌症患者中后部可逆性脑病综合征的发病率有所增加。在这类患者中，诊断具有挑战性。早期识别并开始适当的治疗，去除病因，对于预防永久性神经后遗症至关重要。
