Departamento de Genética, Facultad de Biología, Universidad Complutense de Madrid Madrid, Spain.
Front Plant Sci. 2014 Feb 17;5:23. doi: 10.3389/fpls.2014.00023. eCollection 2014.
Meiotic recombination plays a critical role in achieving accurate chromosome segregation and increasing genetic diversity. Many studies, mostly in yeast, have provided important insights into the coordination and interplay between the proteins involved in the homologous recombination pathway, especially the recombinase RAD51 and the meiosis-specific DMC1. Here we summarize the current progresses on the function of both recombinases and the CX3 complex encoded by AtRAD51 paralogs, in the plant model species Arabidopsis thaliana. Similarities and differences respect to the function of these proteins in other organisms are also indicated.
减数分裂重组在实现染色体正确分离和增加遗传多样性方面起着至关重要的作用。许多研究，主要在酵母中，为同源重组途径中涉及的蛋白质（尤其是重组酶 RAD51 和减数分裂特异性 DMC1）的协调和相互作用提供了重要的见解。在这里，我们总结了植物模式物种拟南芥中两种重组酶和 AtRAD51 同源基因编码的 CX3 复合物的功能的最新进展。还指出了这些蛋白质在其他生物体中的功能的相似之处和差异。
