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双胎反向动脉灌注序列征(TRAP或无心畸胎)——病例报告

Twin Reversed Arterial Perfusion Syndrome (TRAP or Acardiac Twin)-A Case Report.

作者信息

R Kalyani, Bindra Mandeep S

机构信息

Associate Professor, Department of Pathology, ESIC Medical College & PGIMSR , Bangalore, Karnataka, India .

Assistant Professor, Department of Pathology, CMC , Vellore, Tamil nadu, India .

出版信息

J Clin Diagn Res. 2014 Jan;8(1):166-7. doi: 10.7860/JCDR/2014/7012.3965. Epub 2014 Jan 12.

DOI:10.7860/JCDR/2014/7012.3965
PMID:24596758
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3939538/
Abstract

Twin reversed arterial perfusion (TRAP) syndrome is a rare condition (0.3:10,000 births) that occurs in monochorionic twin pregnancies, resulting in coexistence of a normal "pump" twin and an acardiac twin. The acardiac twin is dependent upon the normal twin to provide circulation by means of vascular anastomosis. Many of the bizarre defects are felt to be caused by low oxygen tension and this causes dramatic alteration in the twin fetal physiology and high prenatal mortality. The acardiac twin is a parasite, putting the pump fetus at risk of high output cardiac failure. Overall only 50% of pump twins survive. We present a case in a twenty year female, gravida two, para one, living one, full term normal pregnancy, ultrasound showed twin pregnancy. Following delivery, the first fetus survived only for one day and the second fetus showed features of TRAP syndrome.

摘要

双胎反向动脉灌注(TRAP)综合征是一种罕见病症(发生率为0.3:10,000次分娩),发生于单绒毛膜双胎妊娠,导致正常“泵血”双胎与无心双胎并存。无心双胎依靠正常双胎通过血管吻合提供循环。许多怪异的缺陷被认为是由低氧张力引起的,这导致双胎胎儿生理发生显著改变以及高产前死亡率。无心双胎是一个寄生胎,使泵血胎儿面临高输出量心力衰竭的风险。总体而言,只有50%的泵血双胎存活。我们报告一例20岁女性病例,孕2产1,存活1胎,足月正常妊娠,超声显示双胎妊娠。分娩后,第一个胎儿仅存活一天,第二个胎儿表现出TRAP综合征的特征。

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本文引用的文献

1
Twin reversed arterial perfusion (TRAP) sequence in association with VACTERL association: a case report.双胎反向动脉灌注序列征(TRAP)合并VACTERL综合征:一例报告
J Med Case Rep. 2010 Dec 22;4:411. doi: 10.1186/1752-1947-4-411.
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Placental pathology in trap sequence: clinical and pathogenetic implications.联体双胎序列中的胎盘病理学:临床及发病机制意义
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Twin-reversed arterial perfusion (TRAP) sequence: case reports and review of literature.双胎反向动脉灌注序列征(TRAP):病例报告及文献复习
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