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伴有盆腔侵犯的腹内硬纤维瘤——病例报告

Intra-Abdominal Desmoid Tumour (DT) with Pelvic Extension-A Case Report.

作者信息

Kumar Sathish Selva, Ramachandran Padmini, G Veena, Madhusudhan Napa, Kumbhar Uday

机构信息

Assistant Professor, Department of Pathology, ESI Medical College and Post Graduate Institute of Medical Science and Research (PGIMSR) , Tamil Nadu, India .

Senior Resident, Department of Pathology, ESI Medical College and Post Graduate Institute of Medical Science and Research (PGIMSR) , Tamil Nadu, India .

出版信息

J Clin Diagn Res. 2014 Jan;8(1):168-9. doi: 10.7860/JCDR/2014/7358.3901. Epub 2013 Sep 30.

Abstract

Desmoid Tumour (DT) is a rare benign, myofibroblastic tumour originating from muscle fascia with tendency to recur but, it rarely metastasizes. We are reporting here a case of DT that presented as an intra-abdominal mass with pelvic extension in a patient who underwent hysterectomy for fibroid uterus seventeen years ago. A clinical diagnosis of ovarian malignancy was made. Ovarian tumour markers for surface epithelial and germ cell tumours were negative. Imaging studies suggested DT and the same was excised surgically. A histopathological diagnosis of DT was made and confirmed with immunohistochemistry (IHC) markers. DT should always be considered especially in female patients with previous history of surgery. A complete surgical excision is the treatment of choice with recurrent cases requiring radiotherapy. A differential diagnosis like sarcoma and further toxic chemotherapy can be avoided with careful histopathological evaluation and IHC confirmation of DTs.

摘要

硬纤维瘤(DT)是一种罕见的良性肌成纤维细胞瘤,起源于肌筋膜,有复发倾向,但很少发生转移。我们在此报告一例硬纤维瘤病例,该病例表现为腹腔内肿块并向盆腔扩展,患者17年前因子宫肌瘤接受了子宫切除术。临床诊断为卵巢恶性肿瘤。表面上皮和生殖细胞肿瘤的卵巢肿瘤标志物均为阴性。影像学检查提示为硬纤维瘤,并通过手术切除。经组织病理学诊断为硬纤维瘤,并通过免疫组织化学(IHC)标志物得以证实。尤其是有手术史的女性患者,应始终考虑到硬纤维瘤的可能。完整的手术切除是首选治疗方法,复发病例需要放疗。通过仔细的组织病理学评估和硬纤维瘤的免疫组织化学确认,可以避免肉瘤等鉴别诊断以及进一步的毒性化疗。

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