Groitl H, Scheele J
Chirurgische Klinik, Universität Erlangen-Nürnberg, Federal Republic of Germany.
Surg Endosc. 1987;1(2):93-7. doi: 10.1007/BF00312692.
During a 15-month period, a total of 11 patients underwent endoscopic application of fibrin tissue adhesive in the upper gastrointestinal tract. Our sample consisted of 6 patients with control of bleeding, 4 patients with management of anastomotic leaks, and one very old man undergoing prophylactic sealing of a chronic gastric ulcer with a visible vessel and repeated episodes of bleeding. The method described has proven to be successful in control of bleeding in every case and has resulted in quick cleaning of perianastomotic abscess cavities, growth of granulation tissue, and complete healing in 3 of 4 cases so far. This preliminary report suggests that fibrin adhesive application is effective in the control of oozing gastrointestinal bleeding and may support the healing process in difficult situations, such as chronic peptic ulcers and anastomotic leakages.
在15个月的时间里，共有11例患者接受了上消化道纤维蛋白组织粘合剂的内镜应用。我们的样本包括6例出血得到控制的患者、4例吻合口漏的处理患者以及1例非常年老的男性，该男性接受了对有可见血管且反复出血的慢性胃溃疡的预防性封闭。所描述的方法已被证明在每一例中对出血的控制都是成功的，并且已导致吻合口周围脓肿腔的快速清理、肉芽组织生长，到目前为止4例中有3例完全愈合。这份初步报告表明，纤维蛋白粘合剂的应用在控制胃肠道渗血方面是有效的，并且在诸如慢性消化性溃疡和吻合口漏等困难情况下可能有助于愈合过程。
