Ross Kristie R, Hart Meeghan A
Department of Pediatrics, Rainbow Babies and Children's Hospital and Case Western Reserve University, School of Medicine, Cleveland, OH, USA.
Adolesc Health Med Ther. 2013 Feb 18;4:39-49. doi: 10.2147/AHMT.S26707. eCollection 2013.
The parallel rise in the prevalence of obesity and asthma over the last several decades has led to an extensive line of investigation into the relationship between these two conditions. This review will discuss evidence from laboratory-based studies, observational clinical studies, and clinical trials that suggests that obesity adversely influences asthma through multiple mechanisms. The effect of obesity on asthma during adolescence, including asthma incidence, the severity and control of existing asthma, lung function, and exacerbations, will be reviewed.
在过去几十年里，肥胖症和哮喘的患病率呈平行上升态势，这引发了对这两种疾病之间关系的广泛研究。本综述将讨论来自实验室研究、观察性临床研究和临床试验的证据，这些证据表明肥胖通过多种机制对哮喘产生不利影响。我们将综述肥胖对青少年哮喘的影响，包括哮喘发病率、现有哮喘的严重程度和控制情况、肺功能以及病情加重情况。
