Wiss K, Solomon A R, Raimer S S, Lobe T E, Gourley W, Headington J T
Department of Dermatology, University of Texas Medical Branch, Galveston.
Arch Dermatol. 1988 Nov;124(11):1687-90.
Two patients with rhabdomyosarcoma presented clinically with dermal nodules on the face. The first patient was a 12-month-old girl with a 2 X 3-cm-diameter red nodule on her left cheek that had begun as a small red papule when she was 3 months old and had progressively increased in size. The second patient was a 19-year-old girl who presented with an enlarging mass on her right cheek that had begun as a pea-sized nodule three months previously. In both cases, biopsies revealed a rhabdomyosarcoma in the underlying soft tissue with extension into the overlying dermis. Rhabdomyosarcoma presenting as a dermal nodule is rare. It usually presents as an asymptomatic papule without distinctive clinical features and therefore may result in delayed diagnosis unless a biopsy is performed.
两名横纹肌肉瘤患者临床上均表现为面部皮肤结节。第一名患者是一名12个月大的女孩，左脸颊有一个直径2×3厘米的红色结节，她3个月大时开始是一个小红丘疹，之后逐渐增大。第二名患者是一名19岁女孩，右脸颊有一个不断增大的肿块，3个月前开始是豌豆大小的结节。在这两个病例中，活检均显示皮下软组织有横纹肌肉瘤，并延伸至上方的真皮层。以皮肤结节形式出现的横纹肌肉瘤很罕见。它通常表现为无症状丘疹，无明显临床特征，因此除非进行活检，否则可能导致诊断延迟。
