Tari Ali Sadegh, Amoli Fahimeh Asadi, Rajabi Mohammad Taher, Esfahani Mohammad Riazi, Rahimi Abolfazl
Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Orbit. 2006 Sep;25(3):235-8. doi: 10.1080/01676830600575535.
We report a case of primary cutaneous rhabdomyosarcoma, solid embryonal type, presenting as a rapidly enlarging nodule on the right cheek of a 7-year-old boy. This lesion had begun as a pea-sized nodule 8 months previously, and, with suspected abscess, had been incised. It recurred 2 months later; at that time, incisional biopsy was consistent with malignant round cell tumor. Wide local excision of the tumor was then completed. Subsequent immunohistochemical staining with desmin and myoglobin confirmed embryonal rhabdomyosarcoma. The patient underwent radiation therapy followed by chemotherapy and continues to be disease free at 14 months after his wide local excision. Rhabdomyosarcoma presenting as a dermal nodule is rare. It usually presents as an asymptomatic papule without distinctive clinical features and therefore may result in delayed diagnosis unless a biopsy is performed.
我们报告一例原发性皮肤横纹肌肉瘤，实体胚胎型，表现为一名7岁男孩右脸颊上迅速增大的结节。该病变8个月前开始为豌豆大小的结节，因怀疑脓肿而进行了切开。2个月后复发；当时，切开活检结果与恶性圆形细胞瘤一致。随后完成了肿瘤的广泛局部切除。随后用结蛋白和肌红蛋白进行免疫组化染色，证实为胚胎性横纹肌肉瘤。患者接受了放疗，随后进行化疗，在广泛局部切除术后14个月仍无疾病复发。表现为皮肤结节的横纹肌肉瘤很罕见。它通常表现为无症状丘疹，无明显临床特征，因此除非进行活检，否则可能导致诊断延迟。
