Halaby Reginald
Department of Biology and Molecular Biology, Montclair State University, Montclair USA.
Med Hypothesis Discov Innov Ophthalmol. 2012 Summer;1(2):21-3.
Apoptosis, or programmed cell death, is an integral component of developmental biology, embryology, and anatomy. All eukaryotic cells possess the molecular machinery necessary to execute apoptosis. However, dysregulated apoptosis in the form of too much or too little cell death results in diseases such as Alzheimer's disease, autoimmune disorders, and cancer. It is postulated that apoptosis of the photoreceptors in the retina plays a vital role in mediating vision, and evidence is presented here to support this hypothesis. However, the precise mechanisms that regulate this cell death in photoreceptors have yet to be fully elucidated.
细胞凋亡，即程序性细胞死亡，是发育生物学、胚胎学和解剖学的一个重要组成部分。所有真核细胞都具备执行细胞凋亡所需的分子机制。然而，细胞死亡过多或过少形式的凋亡失调会导致诸如阿尔茨海默病、自身免疫性疾病和癌症等疾病。据推测，视网膜中光感受器的凋亡在介导视觉方面起着至关重要的作用，本文提供了证据来支持这一假设。然而，调节光感受器中这种细胞死亡的精确机制尚未完全阐明。
