Brawer M K, Schifman R B, Ahmann F R, Ahmann M E, Coulis K M
Department of Surgery, University of Arizona, Tucson.
Arch Pathol Lab Med. 1988 Nov;112(11):1110-2.
Serum prostate-specific antigen (PSA) and acid phosphatase (AP) levels were measured before and after digital rectal examination in 26 patients with varying genitourinary complaints. Prostate examination had no effect on the level of these markers. However, AP levels demonstrated greater within-day, intraindividual variance than PSA levels. Digital rectal examination does not appear to be a source of preanalytical error for serum PSA or AP determinations.
对26例有不同泌尿生殖系统症状的患者在直肠指检前后测定了血清前列腺特异性抗原（PSA）和酸性磷酸酶（AP）水平。前列腺检查对这些标志物的水平没有影响。然而，AP水平在日内、个体内的差异比PSA水平更大。直肠指检似乎不是血清PSA或AP测定的分析前误差来源。
