Adjiman S, Zerbib M, Brochard M, Dugue M A, Debré B, Steg A
Clinique Urologique, Hôpital Cochin, Paris.
Ann Urol (Paris). 1989;23(4):291-3.
Prostatic specific antigen has become an essential laboratory parameter in prostatic cancer; it may rise transiently after various manipulations of prostatic tissue. We decided to investigate a possible modification in PSA after rectal examination. The PSA level, studied before and after rectal examination in 40 patients, confirmed the almost constant rise in PSA after thorough rectal examination. The biokinetic features of PSA are also discussed as they are important to determine the time of PSA assay after a transient rise.
前列腺特异性抗原已成为前列腺癌重要的实验室指标；在对前列腺组织进行各种操作后，其水平可能会短暂升高。我们决定研究直肠指检后前列腺特异性抗原（PSA）可能发生的变化。对40例患者在直肠指检前后进行了PSA水平研究，结果证实，在彻底的直肠指检后，PSA几乎持续升高。还讨论了PSA的生物动力学特征，因为它们对于确定PSA短暂升高后进行检测的时间很重要。
