[直肠指检是否会改变前列腺特异性抗原的血液水平？40例病例的研究]

[Does rectal examination modify the blood level of specific prostatic antigen? A study of 40 cases].

作者信息

Adjiman S, Zerbib M, Brochard M, Dugue M A, Debré B, Steg A

机构信息

Clinique Urologique, Hôpital Cochin, Paris.

出版信息

Ann Urol (Paris). 1989;23(4):291-3.

Abstract

Prostatic specific antigen has become an essential laboratory parameter in prostatic cancer; it may rise transiently after various manipulations of prostatic tissue. We decided to investigate a possible modification in PSA after rectal examination. The PSA level, studied before and after rectal examination in 40 patients, confirmed the almost constant rise in PSA after thorough rectal examination. The biokinetic features of PSA are also discussed as they are important to determine the time of PSA assay after a transient rise.

摘要

前列腺特异性抗原已成为前列腺癌重要的实验室指标；在对前列腺组织进行各种操作后，其水平可能会短暂升高。我们决定研究直肠指检后前列腺特异性抗原（PSA）可能发生的变化。对40例患者在直肠指检前后进行了PSA水平研究，结果证实，在彻底的直肠指检后，PSA几乎持续升高。还讨论了PSA的生物动力学特征，因为它们对于确定PSA短暂升高后进行检测的时间很重要。

相似文献

1

[Does rectal examination modify the blood level of specific prostatic antigen? A study of 40 cases].[直肠指检是否会改变前列腺特异性抗原的血液水平？40例病例的研究]

Ann Urol (Paris). 1989;23(4):291-3.

2

The effect of digital rectal examination, flexible cystoscopy and prostatic biopsy on free and total prostate specific antigen, and the free-to-total prostate specific antigen ratio in clinical practice.在临床实践中，直肠指检、软性膀胱镜检查及前列腺活检对游离前列腺特异性抗原、总前列腺特异性抗原以及游离前列腺特异性抗原与总前列腺特异性抗原比值的影响。

J Urol. 1997 May;157(5):1744-7.

3

[Prostate cancer screening using prostate-specific antigen (PSA) determinations in plasma. National Academy of Medicine].[利用血浆中前列腺特异性抗原（PSA）检测进行前列腺癌筛查。美国国家医学院]

Bull Acad Natl Med. 2003;187(5):985-95.

4

[Value of determining prostate-specific antigen for early detection or prostatic carcinoma].[检测前列腺特异性抗原对早期发现前列腺癌的价值]

Urologe A. 1995 Jul;34(4):283-9.

5

[The incidence of the variability of the free PSA/total PSA ratio on the early diagnosis of prostate cancer].[游离前列腺特异性抗原/总前列腺特异性抗原比值变异性在前列腺癌早期诊断中的发生率]

Prog Urol. 1997 Jun;7(3):455-63.

6

Comparison of percent free prostate specific antigen and prostate specific antigen density as methods to enhance prostate specific antigen specificity in early prostate cancer detection in men with normal rectal examination and prostate specific antigen between 4.1 and 10 ng./ml.游离前列腺特异性抗原百分比和前列腺特异性抗原密度作为提高前列腺特异性抗原在直肠指检正常且前列腺特异性抗原水平在4.1至10 ng/ml之间的男性早期前列腺癌检测中特异性的方法的比较

J Urol. 1997 Aug;158(2):502-4.

7

[Significance of PSA-density: analysis in PSA gray zone cases].[前列腺特异抗原密度的意义：前列腺特异抗原灰色区域病例分析]

Hinyokika Kiyo. 2001 Sep;47(9):611-3.

8

[Effect of rectal examination in patients with prostatic adenoma on concentration of prostatic specific antigen (PSA) in plasma].[直肠指检对前列腺腺瘤患者血浆中前列腺特异性抗原（PSA）浓度的影响]

Wiad Lek. 1993 Oct;46(19-20):753-5.

9

The effect of digital rectal examination on serum levels of prostatic-specific antigen.直肠指检对血清前列腺特异性抗原水平的影响。

Arch Pathol Lab Med. 1988 Nov;112(11):1110-2.

10

[Predictive value of prostate specific antigen density in the detection of prostate cancer in patients with elevated prostate specific antigen levels and normal digital rectal findings or stage A prostate cancer].[前列腺特异性抗原密度在前列腺特异性抗原水平升高且直肠指检正常或A期前列腺癌患者前列腺癌检测中的预测价值]

Hinyokika Kiyo. 2001 Mar;47(3):169-74.

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