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韩国妇科医生对子宫内膜癌幸存者激素替代疗法的态度和做法。

Attitudes and practices of Korean gynecologists towards hormone replacement therapy in endometrial cancer survivors.

作者信息

Lee S J, Yeo S G, Kang S B, Park D C

机构信息

Department of Obstetrics and Gynecology, St. Vincent s Hospital, School of Medicine, The Catholic University of Korea, Suwon, Korea.

East-West Medical Research Institutes, Kyung Hee University, Seoul, Korea.

出版信息

Eur J Gynaecol Oncol. 2013;34(6):513-7.

Abstract

PURPOSE

To investigate the attitudes of Korean gynecologists towards prescribing hormone replacement therapy (HRT) after treatment for endometrial cancer.

MATERIALS AND METHODS

A questionnaire, addressing attitudes towards HRT and treatment strategies for patients previously treated for endometrial cancer, was distributed to 163 Korean gynecologists.

RESULTS

Of the 163 gynecologists that were sent this questionnaire, 98 (60.1%) responded. Among the respondents, 81 (82.7%) had previously prescribed HRT to patients with endometrial cancer. Of the latter, 75 (92.6%) had prescribed HRT to patients with Stage I, and more than half to patients with Stage II, endometrial cancer. Of the respondents who had prescribed HRT, 33 (40.7%) did so without regard for cancer-cell type and 33 (40.7%) began patients on HRT more than two years after endometrial cancer treatment. Tibolone was the most commonly prescribed drug (61.9%). The most common reason not to prescribe HRT was fear of cancer recurrence (38.1%).

CONCLUSION

Most of the Korean gynecologists surveyed had experience prescribing HRT to endometrial cancer patients. Although HRT is not actively recommended, HRT given post-therapy to endometrial cancer patients is considered acceptable.

摘要

目的

调查韩国妇科医生对子宫内膜癌治疗后开具激素替代疗法(HRT)的态度。

材料与方法

向163名韩国妇科医生发放了一份问卷,该问卷涉及对HRT的态度以及针对既往接受过子宫内膜癌治疗患者的治疗策略。

结果

在收到这份问卷的163名妇科医生中,98名(60.1%)做出了回应。在受访者中,81名(82.7%)曾给子宫内膜癌患者开具过HRT。其中,75名(92.6%)给I期患者开具过HRT,超过半数给II期子宫内膜癌患者开具过HRT。在开具过HRT的受访者中,33名(40.7%)在开具时未考虑癌细胞类型,33名(40.7%)在子宫内膜癌治疗两年多后才让患者开始接受HRT。替勃龙是最常开具的药物(61.9%)。不开具HRT最常见的原因是担心癌症复发(38.1%)。

结论

大多数接受调查的韩国妇科医生有给子宫内膜癌患者开具HRT的经验。尽管未积极推荐HRT,但子宫内膜癌患者治疗后给予HRT被认为是可以接受的。

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