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使用ABCD2风险评分系统确定因短暂性脑缺血发作就诊于急诊科的患者的短期卒中风险。

Use of ABCD2 risk scoring system to determine the short-term stroke risk in patients presenting to emergency department with transient ischaemic attack.

作者信息

Ozpolat Cigdem, Denizbasi Arzu, Akoglu Haldun, Onur Ozge, Eroglu Serkan Emre, Demir Hasan

机构信息

Department of Emergency Medicine, Marmara University Pendik Education and Research Hospital, Istanbul.

Marmara University Pendik Education and Research Hospital, Istanbul.

出版信息

J Pak Med Assoc. 2013 Sep;63(9):1142-6.

Abstract

OBJECTIVE

To determine the 3-day stroke risk of patients presenting to emergency department with transient ischaemic attack, and to evaluate the predictive value of ABCD(2) (Age, Blood pressure, Clinical features, Duration of symptoms and Diabetes) score for these patients.

METHODS

The prospective study was conducted on patients with diagnosis of transient ischaemic attack who were divided into low (0-3 points), medium (4-5 points) and high (6-7 points) risk groups according to their ABCD(2) scores. The sensitivity of the scoring system on estimation of the risk of stroke in 3 days was evaluated through receiver operating characteristic curve. SPSS 15 was used for data analysis.

RESULTS

Of the 64 patients in the study, none of the low-risk group had stroke. Stroke was present in 4 of 33 (12.12%) medium-risk patients, while there were 4 in 18 (22.22%) in the high-risk group. Sensitivity and specificity of each ABCD(2) score for 3rd day stroke risk was calculated. In the receiver operating curve generated by these calculations, the c statistics was determined as 0.76 (95% CI: 0.64, 0.86; p < 0.01) and the most appropriate cut-off score to dichotomise the study group was determined as 4.

CONCLUSIONS

In transient ischaemic attack patients with an ABCD(2) score of four or higher had a markedly increased short-term stroke risk, while those with a lower score were quite safe. It is appropriate to hospitalise patients with a score of four or more and investigate for underlying cause and initiate treatment.

摘要

目的

确定因短暂性脑缺血发作就诊于急诊科患者的3日卒中风险,并评估ABCD(2)(年龄、血压、临床特征、症状持续时间和糖尿病)评分对这些患者的预测价值。

方法

对诊断为短暂性脑缺血发作的患者进行前瞻性研究,根据其ABCD(2)评分分为低风险(0 - 3分)、中风险(4 - 5分)和高风险(6 - 7分)组。通过受试者工作特征曲线评估评分系统对3日内卒中风险估计的敏感性。使用SPSS 15进行数据分析。

结果

研究中的64例患者中,低风险组无一例发生卒中。中风险组33例中有4例(12.12%)发生卒中,高风险组18例中有4例(22.22%)发生卒中。计算了每个ABCD(2)评分对第3日卒中风险的敏感性和特异性。在这些计算生成的受试者工作曲线中,c统计量确定为0.76(95%CI:0.64,0.86;p < 0.01),将研究组二分的最合适截断分数确定为4分。

结论

ABCD(2)评分在4分及以上的短暂性脑缺血发作患者短期卒中风险显著增加,而评分较低者相当安全。对评分4分及以上的患者进行住院治疗、调查潜在病因并开始治疗是合适的。

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