Certe, Department of Medical Microbiology, Groningen, the Netherlands.
Euro Surveill. 2014 Feb 27;19(8):20711. doi: 10.2807/1560-7917.es2014.19.8.20711.
We describe the results of the Quality Control for Molecular Diagnostics 2013 Neisseria gonorrhoeae external quality assessment programme that included an N. gonorrhoeae strain harbouring an N. meningitidis porA gene which causes false-negative results in molecular diagnostic assays targeting the gonococcal porA pseudogene. Enhanced awareness of the international transmission of such gonococcal strains is needed to avoid false-negative results in both in-house and commercial molecular diagnostic assays used in laboratories worldwide, but particularly in Europe.
我们描述了 2013 年淋病奈瑟菌分子诊断质量控制外部质量评估计划的结果，该计划包括一株淋病奈瑟菌菌株，该菌株携带脑膜炎奈瑟菌 porA 基因，导致针对淋球菌 porA 假基因的分子诊断检测出现假阴性结果。需要增强对这种淋球菌菌株在国际传播的认识，以避免在全球实验室使用的内部和商业分子诊断检测中出现假阴性结果，但在欧洲尤其如此。
