WHO Collaborating Centre for Gonorrhoea and other STIs, Swedish Reference Laboratory for Pathogenic Neisseria, Department of Laboratory Medicine, Microbiology, Orebro University Hospital, Orebro, Sweden.
Euro Surveill. 2012 Mar 1;17(9):20102.
We describe a Neisseria gonorrhoeae strain, found in Sweden in 2011, that harbours a N. meningitidis porA gene causing false-negative results in PCRs targeting the gonococcal porA pseudogene. Furthermore, the strain had no prolyliminopeptidase (PIP) activity that many commercial biochemical kits for species verification in culture rely on. Enhanced awareness of the spread of such strains and screening for them can be crucial.
我们描述了一株淋病奈瑟菌菌株，该菌株于 2011 年在瑞典发现，其携带脑膜炎奈瑟菌 porA 基因，导致针对淋球菌 porA 假基因的 PCR 检测出现假阴性结果。此外，该菌株缺乏许多商业化的基于培养物的种属鉴定用生化试剂盒所依赖的脯氨酰肽酶（PIP）活性。提高对这类菌株传播的认识并对其进行筛查可能至关重要。
