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Recent advances in understanding the pharmacology of amiodarone.

作者信息

Nattel S, Talajic M

机构信息

Department of Medicine, Montreal Heart Institute, Quebec, Canada.

出版信息

Drugs. 1988 Aug;36(2):121-31. doi: 10.2165/00003495-198836020-00001.

DOI:10.2165/00003495-198836020-00001
PMID:2460307
Abstract
摘要

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本文引用的文献

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IPROVERATRIL: EXPERIMENTAL DATA ON CORONARY DILATATION AND ANTIARRHYTHMIC ACTION.异普罗吡胺：关于冠状动脉扩张和抗心律失常作用的实验数据。
Can Med Assoc J. 1964 Mar 28;90(13):761-70.
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Pharmacokinetics of amiodarone after intravenous and oral administration.胺碘酮静脉注射和口服给药后的药代动力学
Eur J Clin Pharmacol. 1981 Mar;19(4):293-9. doi: 10.1007/BF00562807.
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Acute effects of amiodarone upon the canine sinus node and atrioventricular junctional region.胺碘酮对犬窦房结和房室交界区的急性影响。
雷诺嗪：离子通道阻断作用及体内电生理效应。
Br J Pharmacol. 2004 Aug;142(8):1300-8. doi: 10.1038/sj.bjp.0705879. Epub 2004 Jul 26.
4
Dramatic inhibition of amiodarone metabolism induced by grapefruit juice.葡萄柚汁对胺碘酮代谢的显著抑制作用。
Br J Clin Pharmacol. 2000 Apr;49(4):373-8. doi: 10.1046/j.1365-2125.2000.00163.x.
5
Effects of amiodarone on cardiac function and mitochondrial oxidative phosphorylation during ischemia and reperfusion.胺碘酮对缺血再灌注期间心脏功能和线粒体氧化磷酸化的影响。
Mol Cell Biochem. 1999 Apr;194(1-2):291-300. doi: 10.1023/a:1006935323491.
6
Is there a future for antiarrhythmic drug therapy?抗心律失常药物治疗还有未来吗？
Drugs. 1998 Nov;56(5):767-81. doi: 10.2165/00003495-199856050-00003.
7
The treatment of atrial fibrillation. An evaluation of drug therapy, electrical modalities and therapeutic considerations.心房颤动的治疗。药物治疗、电学方法及治疗考量的评估。
Drugs. 1994 Sep;48(3):345-71. doi: 10.2165/00003495-199448030-00003.
8
Antiarrhythmic drug classifications. A critical appraisal of their history, present status, and clinical relevance.抗心律失常药物分类。对其历史、现状及临床相关性的批判性评价。
Drugs. 1991 May;41(5):672-701. doi: 10.2165/00003495-199141050-00002.
9
Amiodarone. An overview of its pharmacological properties, and review of its therapeutic use in cardiac arrhythmias.胺碘酮。其药理特性概述及其在心律失常治疗中的应用综述。
Drugs. 1992 Jan;43(1):69-110. doi: 10.2165/00003495-199243010-00007.
J Clin Invest. 1983 May;71(5):1457-66. doi: 10.1172/jci110899.
4
Clinical pharmacokinetics and efficacy of amiodarone for refractory tachyarrhythmias.胺碘酮治疗难治性快速性心律失常的临床药代动力学及疗效
Circulation. 1983 Jun;67(6):1347-55. doi: 10.1161/01.cir.67.6.1347.
5
Amiodarone-digoxin interaction: clinical significance, time course of development, potential pharmacokinetic mechanisms and therapeutic implications.胺碘酮与地高辛的相互作用：临床意义、发生的时间过程、潜在的药代动力学机制及治疗意义。
J Am Coll Cardiol. 1984 Jul;4(1):111-6. doi: 10.1016/s0735-1097(84)80327-7.
6
Effect of amiodarone on serum quinidine and procainamide levels.胺碘酮对血清奎尼丁和普鲁卡因酰胺水平的影响。
Am J Cardiol. 1984 May 1;53(9):1264-7. doi: 10.1016/0002-9149(84)90076-6.
7
The QT interval: a predictor of the plasma and myocardial concentrations of amiodarone.QT间期：胺碘酮血浆浓度和心肌浓度的预测指标。
Br Heart J. 1984 Mar;51(3):316-20. doi: 10.1136/hrt.51.3.316.
8
A comparison of the electrophysiologic effects of intravenous and oral amiodarone in the same patient.同一患者静脉注射与口服胺碘酮的电生理效应比较。
Circulation. 1984 Jan;69(1):120-4. doi: 10.1161/01.cir.69.1.120.
9
The effects of amiodarone on serum thyroid hormones and hepatic thyroxine 5'-monodeiodination in rats.胺碘酮对大鼠血清甲状腺激素及肝脏甲状腺素5'-单脱碘作用的影响
Endocrinology. 1983 Oct;113(4):1464-9. doi: 10.1210/endo-113-4-1464.
10
Ventricular fibrillation in a conscious canine preparation of sudden coronary death--prevention by short- and long-term amiodarone administration.清醒犬急性冠状动脉性猝死模型中的心室颤动——短期和长期给予胺碘酮的预防作用
Circulation. 1983 Oct;68(4):857-64. doi: 10.1161/01.cir.68.4.857.