特发性中心性浆液性脉络膜视网膜病变脉络膜厚度。
Choroidal thickness in idiopathic subfoveal choroidal neovascularization.
机构信息
Department of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Lab, Beijing, China.
出版信息
Ophthalmologica. 2014;231(4):221-5. doi: 10.1159/000357114. Epub 2014 Mar 5.
PURPOSE
To evaluate choroidal thickness in patients with idiopathic choroidal neovascularization.
METHODS
The observational case series study included patients who were consecutively diagnosed with idiopathic unilateral choroidal neovascularization as demonstrated by ophthalmoscopy, fluorescein angiography and enhanced depth imaging optical coherence tomography (EDI-OCT). Using EDI-OCT, choroidal thickness was measured at the fovea and at locations in a distance of 500, 1,000 and 1,500 μm temporal and nasal to the fovea.
RESULTS
Mean subfoveal choroidal thickness was significantly (p = 0.002) thicker in the study group than in the control group (357 ± 99 vs. 316 ± 83 μm). In a parallel manner, the differences between the study group and the control group in choroidal thickness were significant for all other measurement points, except for the examination at 1,500 μm nasal to the fovea (p = 0.09). The results remained unchanged after adjusting for axial length and age.
CONCLUSIONS
Idiopathic unilateral choroidal neovascularization is associated with a thickening of the choroid.
目的
评估特发性脉络膜新生血管患者的脉络膜厚度。
方法
本观察性病例系列研究纳入了经眼底检查、荧光素血管造影和增强深度成像光学相干断层扫描（EDI-OCT）确诊的特发性单侧脉络膜新生血管患者。使用 EDI-OCT，在黄斑和距黄斑颞侧和鼻侧 500、1000 和 1500μm 处测量脉络膜厚度。
结果
研究组的黄斑下脉络膜厚度明显（p=0.002）比对照组厚（357±99μm 比 316±83μm）。同样，研究组与对照组在所有其他测量点的脉络膜厚度差异均有统计学意义，但距黄斑鼻侧 1500μm 处除外（p=0.09）。在校正眼轴长度和年龄后，结果仍然不变。
结论
特发性单侧脉络膜新生血管与脉络膜增厚有关。
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