Parris W C, Kambam J R, Blanks S, Dean R
Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee.
J Cardiovasc Surg (Torino). 1988 Sep-Oct;29(5):560-2.
Ten patients (Group I) scheduled for major vascular surgery received banked blood and twelve patients (Group II) also scheduled for major vascular surgery were administered intentional hemodilution with autologous blood. Both groups of patients were studied to determine the effects of banked blood and autologous blood respectively on P50. The mean pre-operative P50 for Group I and Group II patients were 26.2 mmHg and 26.3 mmHg respectively. The mean postoperative P50 for Group I and Group II patients were 24.7 mmHg and 28.4 mmHg respectively. There was a significant increase in P50 in patients (Group II) who received autologous blood when compared with Group I patients who received banked blood (p less than 0.001). Our data on P50 in Group I patients who received banked blood showed that there was a significant decrease confirming the results of previously published studies. The Authors conclude that intentional hemodilution is an efficacious alternative technique to banked blood administration for patients undergoing major vascular surgery.
十名计划接受大血管手术的患者（第一组）输注了库存血，另外十二名同样计划接受大血管手术的患者（第二组）进行了自体血预充式血液稀释。对两组患者进行研究，以分别确定库存血和自体血对P50的影响。第一组和第二组患者术前P50的平均值分别为26.2 mmHg和26.3 mmHg。第一组和第二组患者术后P50的平均值分别为24.7 mmHg和28.4 mmHg。与接受库存血的第一组患者相比，接受自体血的患者（第二组）的P50有显著升高（p小于0.001）。我们关于接受库存血的第一组患者P50的数据显示有显著下降，证实了先前发表的研究结果。作者得出结论，对于接受大血管手术的患者，自体血预充式血液稀释是一种有效的替代库存血输注的技术。
