Lagana S, Cattaneo F, Hackenbruch W
Orthopädisch-traumatologische Abteilung, Regionalspital Langenthal.
Swiss Surg. 1996;2(6):244-51.
Although the medical advantages of autologous blood transfusion are undisputed today, it has been established only in a few hospitals. At our hospital we have employed infusion of previously stored autologous blood and normovolemic hemodilution routinely in all patients undergoing major orthopedic surgery since June 1, 1986.
In this study the efficacy of additionally infusing salvaged drainage blood postoperatively in reducing the need for homologous blood transfusion was examined.
From June 1, 1990 through December 30, 1993 the effectiveness of autotransfusion techniques with the additional use of postoperative infusion of salvaged blood was studied in 318 patients.
Preexisting anemia with hemoglobin value of less than 11 g/dl proved to be the only contra-indication for autologous blood transfusions and was found in 8 (2.5%) of our patients. These patients were not eligible for the autologous blood program. The 310 remaining patients were all given their previously stored autologous blood with hemodilution. In addition, 261 of these patients (84%) were also given salvaged drainage blood postoperatively using the solcotrans system or solcotrans-plus-orthopedic system. Of the total 310 patients, 218 (70.3%) did well without homologous blood. This was also true for 206 (78.9%) of the patients treated with all 3 autotransfusion procedures. No complications implicating the autotransfusion techniques were encountered. In addition, the method described and as employed in our hospital led to a cost reduction of about 40% compared to homologous transfusions.
The efficiency of autologous blood transfusions and hemodilution in reducing the need for homologous blood at our hospital, as previously described, could be increased by 22% using the solcotrans system. The advanced age of our patients (average 73 years) and the number of preexisting, in part considerable, medical problems permit the conclusion that these autotransfusion techniques are quite well tolerated. The contraindications could be reduced to a few exceptions. The logistics necessary to carry out these procedures are simple and can be achieved with a bit of will and effort in all hospitals including those of middle and small size.
尽管自体输血的医学优势如今已无可争议,但仅在少数医院得以应用。自1986年6月1日起,我院在所有接受大型骨科手术的患者中常规采用输注预先储存的自体血和等容血液稀释法。
本研究旨在探讨术后额外输注回收引流血在减少同种异体输血需求方面的疗效。
1990年6月1日至1993年12月30日期间,对318例患者研究了自体输血技术联合术后输注回收血的有效性。
血红蛋白值低于11g/dl的既往贫血被证明是自体输血的唯一禁忌症,在我们的患者中有8例(2.5%)存在该情况。这些患者不符合自体输血计划的条件。其余310例患者均接受了预先储存的自体血和血液稀释。此外,这些患者中有261例(84%)术后还使用索科输血系统或索科输血-骨科联合系统输注了回收引流血。在总共310例患者中,218例(70.3%)未接受同种异体输血情况良好。接受所有三种自体输血程序治疗的患者中,206例(78.9%)也是如此。未遇到与自体输血技术相关的并发症。此外,我院所描述和采用的方法与同种异体输血相比,成本降低了约40%。
如前所述,使用索科输血系统可使我院自体输血和血液稀释在减少同种异体输血需求方面的效率提高22%。我们患者的高龄(平均73岁)以及存在的一些既往医疗问题(部分问题较为严重)使得我们可以得出结论,这些自体输血技术耐受性良好。禁忌症可减少至少数例外情况。实施这些程序所需的后勤工作简单,所有医院,包括中小型医院,只要有一点意愿和努力就能做到。