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Editorial commentary: Host-pathogen interactions in Clostridium difficile infection: it takes two to tango.

作者信息

Aronoff David M

机构信息

Division of Infectious Diseases, Department of Medicine, Vanderbilt University, Nashville, Tennessee.

出版信息

Clin Infect Dis. 2014 May;58(10):1401-3. doi: 10.1093/cid/ciu141. Epub 2014 Mar 5.

Abstract
摘要

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NAP1 strain type predicts outcomes from Clostridium difficile infection.
Clin Infect Dis. 2014 May;58(10):1394-400. doi: 10.1093/cid/ciu125. Epub 2014 Mar 5.
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Clostridium difficile toxin CDT hijacks microtubule organization and reroutes vesicle traffic to increase pathogen adherence.
Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2313-8. doi: 10.1073/pnas.1311589111. Epub 2014 Jan 27.
3
Clostridium difficile infection in the elderly.
Clin Geriatr Med. 2014 Feb;30(1):79-93. doi: 10.1016/j.cger.2013.10.008.
4
Poor functional status as a risk factor for severe Clostridium difficile infection in hospitalized older adults.
J Am Geriatr Soc. 2013 Oct;61(10):1738-42. doi: 10.1111/jgs.12442. Epub 2013 Sep 19.
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Clostridium difficile 027/BI/NAP1 encodes a hypertoxic and antigenically variable form of TcdB.
PLoS Pathog. 2013;9(8):e1003523. doi: 10.1371/journal.ppat.1003523. Epub 2013 Aug 1.
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Understanding increased mortality in Clostridium difficile-infected older adults.
Clin Infect Dis. 2013 Aug;57(4):625-6. doi: 10.1093/cid/cit310. Epub 2013 May 8.
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Attributable burden of hospital-onset Clostridium difficile infection: a propensity score matching study.
Infect Control Hosp Epidemiol. 2013 Jun;34(6):588-96. doi: 10.1086/670621. Epub 2013 Apr 19.
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The relationship between phenotype, ribotype, and clinical disease in human Clostridium difficile isolates.
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Emergence and global spread of epidemic healthcare-associated Clostridium difficile.
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