• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

美国六家医疗机构艰难梭菌核糖体分型多样性研究。

Clostridium difficile ribotype diversity at six health care institutions in the United States.

机构信息

Department of Internal Medicine, Division of Infectious Diseases, University of Michigan Hospital and Health Systems, Ann Arbor, Michigan, USA.

出版信息

J Clin Microbiol. 2013 Jun;51(6):1938-41. doi: 10.1128/JCM.00056-13. Epub 2013 Apr 3.

DOI:10.1128/JCM.00056-13
PMID:23554188
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3716112/
Abstract

Capillary-based PCR ribotyping was used to quantify the presence/absence and relative abundance of 98 Clostridium difficile ribotypes from clinical cases of disease at health care institutions in six states of the United States. Regionally important ribotypes were identified, and institutions in close proximity did not necessarily share more ribotype diversity than institutions that were farther apart.

摘要

基于毛细管的 PCR 核糖体分型技术用于定量检测美国六个州医疗机构中 98 种艰难梭菌核糖体分型的存在/缺失和相对丰度。确定了具有地区重要性的核糖体分型，并且近距离的机构不一定比远距离的机构具有更多的核糖体分型多样性。

相似文献

1
Clostridium difficile ribotype diversity at six health care institutions in the United States.美国六家医疗机构艰难梭菌核糖体分型多样性研究。
J Clin Microbiol. 2013 Jun;51(6):1938-41. doi: 10.1128/JCM.00056-13. Epub 2013 Apr 3.
2
Use of modified PCR ribotyping for direct detection of Clostridium difficile ribotypes in stool samples.应用改良 PCR 核糖体分型技术直接检测粪便样本中的艰难梭菌核糖体分型。
J Clin Microbiol. 2011 Aug;49(8):3024-5. doi: 10.1128/JCM.01013-11. Epub 2011 Jun 1.
3
Predominance of PCR-ribotypes, 018 (smz) and 369 (trf) of Clostridium difficile in Japan: a potential relationship with other global circulating strains?日本艰难梭菌PCR核糖体分型018（smz）和369（trf）的优势：与其他全球流行菌株是否存在潜在关系？
J Med Microbiol. 2015 Oct;64(10):1226-1236. doi: 10.1099/jmm.0.000149. Epub 2015 Jul 31.
4
Molecular epidemiology of Clostridium difficile strains in children compared with that of strains circulating in adults with Clostridium difficile-associated infection.比较儿童艰难梭菌菌株与成人艰难梭菌相关性感染中流行的菌株的分子流行病学。
J Clin Microbiol. 2011 Nov;49(11):3994-6. doi: 10.1128/JCM.05349-11. Epub 2011 Sep 21.
5
An Observational Cohort Study of Ribotype 027 and Recurrent Infection.027 型与再感染的观察性队列研究。
mSphere. 2018 May 23;3(3). doi: 10.1128/mSphere.00033-18. eCollection 2018 May-Jun.
6
PCR ribotypes of across Texas from 2011 to 2018 including emergence of ribotype 255.2011 年至 2018 年期间，德克萨斯州的 255 型核糖体型的出现。
Emerg Microbes Infect. 2020 Feb 10;9(1):341-347. doi: 10.1080/22221751.2020.1721335. eCollection 2020.
7
An enhanced DNA fingerprinting service to investigate potential Clostridium difficile infection case clusters sharing the same PCR ribotype.一种增强型 DNA 指纹图谱服务，用于调查具有相同 PCR 核糖体分型的潜在艰难梭菌感染病例聚集。
J Clin Microbiol. 2011 Dec;49(12):4333-7. doi: 10.1128/JCM.05873-11. Epub 2011 Sep 28.
8
Correlation between restriction endonuclease analysis and PCR ribotyping for the identification of Clostridioides (Clostridium) difficile clinical strains.用于鉴定艰难梭菌临床菌株的限制性内切酶分析与PCR核糖体分型之间的相关性
Anaerobe. 2018 Dec;54:1-7. doi: 10.1016/j.anaerobe.2018.07.004. Epub 2018 Aug 3.
9
Challenges for standardization of Clostridium difficile typing methods.艰难梭菌分型方法标准化面临的挑战。
J Clin Microbiol. 2013 Sep;51(9):2810-4. doi: 10.1128/JCM.00143-13. Epub 2013 Jun 19.
10
To the Editor: Molecular epidemiology of toxigenic Clostridium difficile isolates in Korea.致编辑：韩国产毒艰难梭菌分离株的分子流行病学
Epidemiol Infect. 2014 Aug;142(8):1651-2. doi: 10.1017/S0950268813003051. Epub 2013 Dec 2.

引用本文的文献

1
Phenotypic analysis of various ribotypes reveals consistency among core processes.对各种核糖体分型的表型分析揭示了核心过程之间的一致性。
Appl Environ Microbiol. 2025 Jun 24:e0096425. doi: 10.1128/aem.00964-25.
2
Phenotypic analysis of various ribotypes reveals consistency among core processes.对各种核糖型的表型分析揭示了核心过程之间的一致性。
bioRxiv. 2025 Jan 10:2025.01.10.632434. doi: 10.1101/2025.01.10.632434.
3
Sentinel surveillance and epidemiology of in Denmark, 2016 to 2019.丹麦 2016 至 2019 年 监测和流行病学研究
Euro Surveill. 2022 Dec;27(49). doi: 10.2807/1560-7917.ES.2022.27.49.2200244.
4
Functional analyses of epidemic Clostridioides difficile toxin B variants reveal their divergence in utilizing receptors and inducing pathology.流行的艰难梭菌毒素 B 变体的功能分析揭示了它们在利用受体和诱导病理方面的差异。
PLoS Pathog. 2021 Jan 28;17(1):e1009197. doi: 10.1371/journal.ppat.1009197. eCollection 2021 Jan.
5
Retrospective Definition of PCR Ribotypes on the Basis of Whole Genome Polymorphisms: A Proof of Principle Study.基于全基因组多态性的PCR核糖型回顾性定义：一项原理验证研究
Diagnostics (Basel). 2020 Dec 12;10(12):1078. doi: 10.3390/diagnostics10121078.
6
Homologous Recombination in Mediates Diversification of Cell Surface Features and Transport Systems.同源重组在 中介导细胞表面特征和运输系统的多样化。
mSphere. 2020 Nov 18;5(6):e00799-20. doi: 10.1128/mSphere.00799-20.
7
Clostridioides difficile infection in US hospitals: a national inpatient sample study.美国医院艰难梭菌感染：全国住院患者样本研究。
Int J Colorectal Dis. 2020 Oct;35(10):1929-1935. doi: 10.1007/s00384-020-03646-3. Epub 2020 Jun 17.
8
Biological characteristics associated with virulence in ribotype 002 in Hong Kong.与香港 002 型菌株毒力相关的生物学特性。
Emerg Microbes Infect. 2020 Mar 17;9(1):631-638. doi: 10.1080/22221751.2020.1739564. eCollection 2020.
9
Proteotyping of as Alternate Typing Method to Ribotyping Is Able to Distinguish the Ribotypes RT027 and RT176 From Other Ribotypes.将蛋白质分型作为核糖体分型的替代分型方法能够区分核糖体分型RT027和RT176与其他核糖体分型。
Front Microbiol. 2019 Sep 10;10:2087. doi: 10.3389/fmicb.2019.02087. eCollection 2019.
10
ribotype 017 - characterization, evolution and epidemiology of the dominant strain in Asia.ribotype 017-亚洲主要流行株的特征、进化和流行病学研究。
Emerg Microbes Infect. 2019;8(1):796-807. doi: 10.1080/22221751.2019.1621670.

本文引用的文献

1
Detection of mixed populations of Clostridium difficile from symptomatic patients using capillary-based polymerase chain reaction ribotyping.应用基于毛细管的聚合酶链反应核糖体分型技术检测有症状患者中艰难梭菌的混合种群。
Infect Control Hosp Epidemiol. 2013 Sep;34(9):961-966. doi: 10.1086/671728. Epub 2013 Jul 12.
2
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.艰难梭菌感染的诊断、治疗和预防指南。
Am J Gastroenterol. 2013 Apr;108(4):478-98; quiz 499. doi: 10.1038/ajg.2013.4. Epub 2013 Feb 26.
3
Clostridium difficile ribotype does not predict severe infection.艰难梭菌核糖体分型不能预测严重感染。
Clin Infect Dis. 2012 Dec;55(12):1661-8. doi: 10.1093/cid/cis786. Epub 2012 Sep 12.
4
Changing epidemiology of Clostridium difficile infection following the introduction of a national ribotyping-based surveillance scheme in England.在英国引入基于核糖体分型的全国监测计划后，艰难梭菌感染的流行病学发生变化。
Clin Infect Dis. 2012 Oct;55(8):1056-63. doi: 10.1093/cid/cis614. Epub 2012 Jul 11.
5
Comparative analysis of an expanded Clostridium difficile reference strain collection reveals genetic diversity and evolution through six lineages.比较分析扩展的艰难梭菌参考菌株集揭示了通过六个谱系的遗传多样性和进化。
Infect Genet Evol. 2012 Oct;12(7):1577-85. doi: 10.1016/j.meegid.2012.06.003. Epub 2012 Jun 15.
6
Non-toxigenic Clostridium sordellii: clinical and microbiological features of a case of cholangitis-associated bacteremia.无细胞毒素梭状芽胞杆菌：与胆管炎相关的菌血症病例的临床和微生物学特征。
Anaerobe. 2011 Oct;17(5):252-6. doi: 10.1016/j.anaerobe.2011.06.009. Epub 2011 Jun 25.
7
Clostridium difficile infection in Europe: a hospital-based survey.欧洲艰难梭菌感染：一项基于医院的调查。
Lancet. 2011 Jan 1;377(9759):63-73. doi: 10.1016/S0140-6736(10)61266-4.
8
Investigation of toxin gene diversity, molecular epidemiology, and antimicrobial resistance of Clostridium difficile isolated from 12 hospitals in South Korea.对从韩国12家医院分离出的艰难梭菌的毒素基因多样性、分子流行病学及抗菌药物耐药性的调查。
Korean J Lab Med. 2010 Oct;30(5):491-7. doi: 10.3343/kjlm.2010.30.5.491.
9
Impact of strain type on detection of toxigenic Clostridium difficile: comparison of molecular diagnostic and enzyme immunoassay approaches.菌株类型对产毒艰难梭菌检测的影响：分子诊断与酶免疫分析方法的比较。
J Clin Microbiol. 2010 Oct;48(10):3719-24. doi: 10.1128/JCM.00427-10. Epub 2010 Aug 11.
10
Health care-associated Clostridium difficile infection in Canada: patient age and infecting strain type are highly predictive of severe outcome and mortality.加拿大与医疗保健相关的艰难梭菌感染：患者年龄和感染菌株类型与严重结局和死亡率高度相关。
Clin Infect Dis. 2010 Jan 15;50(2):194-201. doi: 10.1086/649213.