Department of Internal Medicine, Division of Infectious Diseases, University of Michigan Hospital and Health Systems, Ann Arbor, Michigan, USA.
J Clin Microbiol. 2013 Jun;51(6):1938-41. doi: 10.1128/JCM.00056-13. Epub 2013 Apr 3.
Capillary-based PCR ribotyping was used to quantify the presence/absence and relative abundance of 98 Clostridium difficile ribotypes from clinical cases of disease at health care institutions in six states of the United States. Regionally important ribotypes were identified, and institutions in close proximity did not necessarily share more ribotype diversity than institutions that were farther apart.
基于毛细管的 PCR 核糖体分型技术用于定量检测美国六个州医疗机构中 98 种艰难梭菌核糖体分型的存在/缺失和相对丰度。确定了具有地区重要性的核糖体分型,并且近距离的机构不一定比远距离的机构具有更多的核糖体分型多样性。