Expert Rev Vaccines. 2014 Apr;13(4):533-44. doi: 10.1586/14760584.2014.894468.
Human papillomavirus (HPV) is the primary cause of cervical cancer and genital warts. The development of HPV vaccines has been a major advance in the prevention of these diseases. Recent studies have shown promising early effects of HPV immunization programs on cervical abnormalities and genital warts, with evidence of herd immunity against genital warts also emerging in Australia. Further studies are required to not only continue monitoring the effect of the HPV immunization on the incidence of these diseases, but also to establish the effect the immunization will have on cervical screening programs and the performance of colposcopy.
人乳头瘤病毒(HPV)是宫颈癌和生殖器疣的主要病因。HPV 疫苗的开发是预防这些疾病的重大进展。最近的研究表明,HPV 免疫计划对宫颈异常和生殖器疣具有早期的显著效果,并且在澳大利亚也出现了针对生殖器疣的群体免疫证据。还需要进一步的研究,不仅要继续监测 HPV 免疫对这些疾病发病率的影响,还要确定免疫对宫颈筛查计划和阴道镜检查的效果。