一种用于活细胞中硫化氢成像的比率荧光探针。
A ratiometric fluorescent probe for hydrogen sulfide imaging in living cells.
作者信息
Jiang Yin, Wu Qiong, Chang Xijun
机构信息
Department of Chemistry, Lanzhou University, Lanzhou 730000, PR China.
Lanzhou Jinchuan Advanced Materials Technology Co. Ltd., Lanzhou 730101, PR China.
出版信息
Talanta. 2014 Apr;121:122-6. doi: 10.1016/j.talanta.2014.01.001. Epub 2014 Jan 8.
We herein report a turn-on fluorescent probe based on excited state intramolecular proton transfer (ESIPT) mechanism and self-immolative linker for hydrogen sulfide detection. The new probe exhibits high sensitivity and selectivity over other biologically relevant anions. Moreover, we show the utility of the probe for the detection of hydrogen sulfide in living cells as well.
我们在此报告一种基于激发态分子内质子转移（ESIPT）机制和自毁连接体的用于硫化氢检测的开启型荧光探针。该新型探针相对于其他生物相关阴离子表现出高灵敏度和选择性。此外，我们还展示了该探针在活细胞中检测硫化氢的实用性。
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