Baroni R, Guidi L, Bartoloni C, Gambassi G
Facoltà di Medicina e Chirurgia, Università Cattolica del Sacro Cuore, Roma.
Minerva Med. 1988 Oct;79(10):839-44.
A number of the mechanisms implicated in the phenomenon of immunosuppression present in tumour-carrying patients are described. In particular, stress is laid on factors soluble to immunosuppressive activity identified in the serum or in other biological fluids of these patients. From among these are analysed the circulating immunocomplexes, the proteins of the acute phase (alpha-globulins) and other inhibiting substances derived from tumour cells. The nature and origin of these substances are discussed as well as their effects on the cancer patient's immune system and the therapeutic type implications that arise in some cases.
本文描述了一些与肿瘤患者免疫抑制现象相关的机制。特别强调了在这些患者的血清或其他生物体液中发现的具有免疫抑制活性的可溶性因素。其中分析了循环免疫复合物、急性期蛋白（α球蛋白）以及其他源自肿瘤细胞的抑制物质。讨论了这些物质的性质和来源，以及它们对癌症患者免疫系统的影响和某些情况下产生的治疗类型的影响。
