Segal-Eiras A, Croce M V
Allergol Immunopathol (Madr). 1984 May-Jun;12(3):225-32.
This paper is a review on immune complexes in malignant tumours. High levels of immune complexes have been detected in the serum of patients with malignant solid tumours, leukemias and lymphomas. These studies were performed using non-specific methods. Results obtained by different laboratories are in general coincident; elevated levels of immune complexes in pre-treatment samples and in recurrent disease and, normal values in post-treatment studies indicating a disease free state. Nevertheless, there are certain variations among the results obtained by different techniques suggesting the necessity to check various methods for each tumour type. Although there is no clear evidence that immune complexes in cancer patients contain tumor related products, the current status of clinical research suggests the potential of circulating immune complexes assays for monitoring malignant diseases.
本文是一篇关于恶性肿瘤中免疫复合物的综述。在恶性实体瘤、白血病和淋巴瘤患者的血清中已检测到高水平的免疫复合物。这些研究采用的是非特异性方法。不同实验室获得的结果总体上是一致的；治疗前样本和复发疾病中免疫复合物水平升高，而治疗后研究中的正常数值表明处于无病状态。然而，不同技术获得的结果之间存在一定差异，这表明有必要针对每种肿瘤类型检查各种方法。尽管没有明确证据表明癌症患者的免疫复合物含有肿瘤相关产物，但临床研究的现状表明循环免疫复合物检测在监测恶性疾病方面具有潜力。
