Tschen J A, McGavran M H, Kettler A H
Department of Pathology, Baylor College of Medicine, Houston, TX 77030.
J Am Acad Dermatol. 1988 Nov;19(5 Pt 1):891-4. doi: 10.1016/s0190-9622(88)70250-9.
Pale cells that resemble those of Paget's disease have been found within apparently normal epidermis in a variety of benign papules. Although they have been considered an artifact, they show characteristic premature keratinization. In contrast to other dyskeratotic processes they mature into orthokeratotic squamae. The histopathologic, ultrastructural and immunocytochemical features of these cells are illustrated, and the differential diagnosis is reviewed.
在多种良性丘疹的看似正常的表皮内发现了类似于佩吉特病细胞的苍白细胞。尽管它们曾被认为是一种假象，但却显示出特征性的过早角化。与其他角化异常过程不同，它们成熟为正角化鳞状细胞。本文阐述了这些细胞的组织病理学、超微结构和免疫细胞化学特征，并对鉴别诊断进行了综述。
