免疫学期刊：移植中的调节性 T 细胞——一把双刃剑？
Immunology: TREG cells in transplantation-a double-edged sword?
机构信息
Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine and University of Pittsburgh Medical Center, BST-W1548, 200 Lothrop Street, Pittsburgh, PA 15261, USA.
出版信息
Nat Rev Nephrol. 2014 Apr;10(4):185-6. doi: 10.1038/nrneph.2014.35. Epub 2014 Mar 11.
PMID:24614404
Abstract
Immunosuppressive drugs commonly used in transplantation and autoimmune diseases are unfortunately associated with increased cancer incidence. Now, a new study reports a direct relationship between the number of regulatory T cells in the blood and the risk of developing invasive skin cancer in kidney transplant recipients.
摘要
免疫抑制药物在移植和自身免疫性疾病中通常被广泛应用，但不幸的是，这些药物会增加癌症的发病率。现在，一项新的研究报告称，血液中调节性 T 细胞的数量与肾移植受者发生侵袭性皮肤癌的风险直接相关。
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