Tsuruta Y, Miyahara H, Sato T, Yoshino K, Umatani K
Dept. of Otolaryngology, Head & Neck Surgery, Center for Adult Diseases, Osaka.
Gan No Rinsho. 1988 Oct;34(12):1693-8.
A 55-year-old male with a mesopharyngeal carcinoma (squamous cell carcinoma) T3N3N0 and a pulmonary carcinoma (adenocarcinoma) T3N2M0 was treated with induction chemotherapy, consisting of cisplatin (100 mg/body), bleomycin (30 mg/body), and methotrexate (40 mg/body), that was followed by a radical neck dissection of the cervical metastatic lesion. After two courses of chemotherapy, both the primary and nodal lesions of the mesopharyngeal carcinoma showed a complete response and, histologically, no evidence of any viable tumor cells remained. The patient died, however, due to the pulmonary carcinoma two years and seven months after his first treatment. An autopsy revealed no evidence of the squamous cell carcinoma. In this case, the squamous cell carcinoma of the mesopharynx and the cervical lymph nodes showed a radically good response to treatment by chemotherapy.
一名55岁男性，患有中咽癌（鳞状细胞癌）T3N3N0和肺癌（腺癌）T3N2M0，接受了诱导化疗，化疗方案为顺铂（100mg/体）、博来霉素（30mg/体）和甲氨蝶呤（40mg/体），随后对颈部转移病灶进行了根治性颈清扫术。经过两个疗程的化疗，中咽癌的原发灶和淋巴结病灶均显示完全缓解，组织学检查未发现任何存活肿瘤细胞。然而，患者在首次治疗两年零七个月后因肺癌死亡。尸检未发现鳞状细胞癌的证据。在本病例中，中咽鳞状细胞癌和颈部淋巴结对化疗显示出良好的根治性反应。
