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1例阴囊癌伴腹股沟淋巴结转移经多学科治疗,包括使用甲氨蝶呤、博来霉素和顺铂化疗

[A case of scrotal cancer with inguinal lymph node metastasis treated by multidisciplinary modalities including chemotherapy with methotrexate, bleomycin and cisplatin].

作者信息

Arai Y, Kinouchi T, Kuroda M, Usami M, Kotake T

机构信息

Department of Urology, Osaka Medical Center for Cancer and Cardiovascular Diseases.

出版信息

Hinyokika Kiyo. 1997 Sep;43(9):683-5.

PMID:9365852
Abstract

We report a case of scrotum with inguinal lymph node metastasis which was successfully treated by multidisciplinary modalities including combination chemotherapy and radiotherapy. A 60-year-old man was admitted with ulcerative induration of the scrotum and inguinal lymph node swelling. Biopsy of the scrotal skin showed squamous cell carcinoma. He received 4 courses of combination chemotherapy with methotrexate, bleomycin and cisplatin. The primary lesion disappeared macroscopically and metastatic lymphadenopathy showed 50% reduction in size. Both lesions were further treated with radiotherapy (60 Gy). Because the primary lesion became ulcerative 7 months after irradiation, partial resection of the scrotum was performed. He has been free of recurrence 22 months after chemotherapy.

摘要

我们报告一例阴囊伴腹股沟淋巴结转移的病例,该病例通过包括联合化疗和放疗在内的多学科治疗方式成功治愈。一名60岁男性因阴囊溃疡性硬结和腹股沟淋巴结肿大入院。阴囊皮肤活检显示为鳞状细胞癌。他接受了4个疗程的甲氨蝶呤、博来霉素和顺铂联合化疗。原发灶肉眼可见消失,转移性淋巴结肿大缩小了50%。两个病灶均进一步接受了放疗(60 Gy)。由于放疗7个月后原发灶出现溃疡,遂行阴囊部分切除术。化疗后22个月他一直无复发。

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