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虹鳟鱼和人类高密度脂蛋白中共同抗原位点的免疫学证据。

Immunological evidence for common antigenic sites in high-density lipoproteins from rainbow trout and man.

作者信息

Ayrault-Jarrier M, Burdin J, Fremont L, Gozzelino M T

机构信息

U.A. 524 CNRS, Laboratoire de Biochimie, Faculté de Médecine Saint-Antoine, Paris, France.

出版信息

Biochem J. 1988 Sep 15;254(3):927-30. doi: 10.1042/bj2540927.

DOI:10.1042/bj2540927
PMID:2461703
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1135175/
Abstract

The plasma high-density lipoproteins (HDL, rho 1.085-1.21 g/ml) of rainbow trout (Salmo gairdneri) have been shown to contain large amounts of apolipoprotein (apo) AI (Mr 28,000) and several other apolipoproteins of Mr less than 14,000 (apo C-like) and of Mr 37,000-38,000, 44,000-45,000 and 53,000-54,000. Comparison of apo AI from trout and human HDL shows them to be similar in Mr and to have some cross-immunoreactivity, whereas apo AII differs in Mr but also possesses common antigenic sites. It is suggested that the major apolipoproteins of fish and human HDL may fulfil similar roles in lipid transport.

摘要

虹鳟鱼(Salmo gairdneri)的血浆高密度脂蛋白(HDL,密度1.085 - 1.21 g/ml)已被证明含有大量载脂蛋白(apo)AI(分子量28,000)以及其他几种分子量小于14,000的载脂蛋白(类apo C)和分子量为37,000 - 38,000、44,000 - 45,000和53,000 - 54,000的载脂蛋白。对虹鳟鱼和人类HDL中的apo AI进行比较发现,它们的分子量相似且具有一些交叉免疫反应性,而apo AII的分子量不同但也具有共同的抗原位点。有人提出,鱼类和人类HDL的主要载脂蛋白在脂质转运中可能发挥相似的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61ec/1135175/4e14701927dd/biochemj00223-0288-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61ec/1135175/b061bdfb1cab/biochemj00223-0287-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61ec/1135175/7899dc8dcfcc/biochemj00223-0287-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61ec/1135175/e5855b3ae284/biochemj00223-0288-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61ec/1135175/079e34be77ab/biochemj00223-0288-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61ec/1135175/4e14701927dd/biochemj00223-0288-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61ec/1135175/b061bdfb1cab/biochemj00223-0287-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61ec/1135175/7899dc8dcfcc/biochemj00223-0287-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61ec/1135175/e5855b3ae284/biochemj00223-0288-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61ec/1135175/079e34be77ab/biochemj00223-0288-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61ec/1135175/4e14701927dd/biochemj00223-0288-c.jpg

相似文献

1
Immunological evidence for common antigenic sites in high-density lipoproteins from rainbow trout and man.虹鳟鱼和人类高密度脂蛋白中共同抗原位点的免疫学证据。
Biochem J. 1988 Sep 15;254(3):927-30. doi: 10.1042/bj2540927.
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