Pradeep B Vishwanath, Tejaswini M, Nishal P, Pardhu G, Shylaja S, Kumar Kranthi Ch
J Environ Biol. 2013 May;34(3):645-9.
Natural products continue to play an important role in the discovery and development of new pharmaceuticals. Several chemical compounds have been extracted and identified from its species known as Lantana camara (L .camara). The present study was designed for phytochemical analysis of L. camara and extraction of bioactive compound by HPLC. This also included the antimicrobial activity of the bioactive compound obtained by crude extract and the column extract. The study showed the presence of the bioactive component parthenin extracted from the HPLC analysis at a peak height of 10.3807 and it was showing antimicrobial activity against E. coli, P. aeruginosa, B. subtilis and E. fecalis, crude (6.8 to 8.1 mm ) and column (4.0 to 6.2 mm) zone of inhibition.
天然产物在新药物的发现和开发中继续发挥着重要作用。已经从名为马缨丹（Lantana camara，L. camara）的植物物种中提取并鉴定出了几种化合物。本研究旨在对马缨丹进行植物化学分析，并通过高效液相色谱法提取生物活性化合物。这还包括粗提物和柱提取物中获得的生物活性化合物的抗菌活性。研究表明，通过高效液相色谱分析在峰高为10.3807时提取到了生物活性成分小白菊内酯，它对大肠杆菌、铜绿假单胞菌、枯草芽孢杆菌和粪肠球菌具有抗菌活性，粗提物的抑菌圈为（6.8至8.1毫米），柱提取物的抑菌圈为（4.0至6.2毫米）。
