Kang Longli, Wang Chuan-Chao, Chen Feng, Yao Dali, Jin Li, Li Hui
a Key Laboratory of High Altitude Environment and Gene Related to Disease of Tibet , Ministry of Education, Tibet University for Nationalities , Xianyang , Shaanxi , China and.
b Ministry of Education Key Laboratory of Contemporary Anthropology , School of Life Sciences, Fudan University , Shanghai , China.
Mitochondrial DNA A DNA Mapp Seq Anal. 2016;27(1):342-9. doi: 10.3109/19401736.2014.895986. Epub 2015 Sep 4.
The Himalayas have been suggested as a natural barrier for human migrations, especially the northward dispersals from the Indian Subcontinent to Tibetan Plateau. However, although the majority of Sherpa have a Tibeto-Burman origin, considerable genetic components from Indian Subcontinent have been observed in Sherpa people living in Tibet. The western Y chromosomal haplogroups R1a1a-M17, J-M304, and F*-M89 comprise almost 17% of Sherpa paternal gene pool. In the maternal side, M5c2, M21d, and U from the west also count up to 8% of Sherpa people. Those lineages with South Asian origin indicate that the Himalayas have been permeable to bidirectional gene flow.
喜马拉雅山脉被认为是人类迁徙的天然屏障，尤其是从印度次大陆向北扩散到青藏高原。然而，尽管大多数夏尔巴人起源于藏缅语族，但在居住在西藏的夏尔巴人中发现了相当多来自印度次大陆的基因成分。西部的Y染色体单倍群R1a1a-M17、J-M304和F*-M89几乎占夏尔巴父系基因库的17%。在母系方面，来自西部的M5c2、M21d和U也占夏尔巴人的8%。这些起源于南亚的谱系表明，喜马拉雅山脉对双向基因流动具有通透性。
