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埃及单中心强直性脊柱炎患者工作残疾的患病率及其相关危险因素。

Prevalence and associated risk factors for work disability in Egyptian patients with ankylosing spondylitis from one center.

机构信息

Department of Rheumatology and Rehabilitation, Zagazig University, Zagazig, Egypt.

Department of Community, Environmental and Occupational Medicine, Zagazig University, Zagazig, Egypt.

出版信息

Int J Rheum Dis. 2017 Dec;20(12):2028-2034. doi: 10.1111/1756-185X.12306. Epub 2014 Feb 15.

DOI:10.1111/1756-185X.12306
PMID:24618084
Abstract

OBJECTIVE

To determine the prevalence of work disability (WD) in Egyptian patients with ankylosing spondylitis (AS) and to identify the main factors associated with this.

METHODS

A cross-sectional survey was conducted among all patients with AS during an extended outpatient visit in the period between July, 2011 and December, 2012. Demographic data were collected and a physical examination was performed. Multivariate modeling was applied to determine the factors associated with work disability.

RESULTS

The questionnaire was completed by 90 patients (85 males; 94.4%). The mean age of the participants was 37.8 (SD 9.7) years, mean disease duration was 12.1 (SD 8.9) years, and the mean symptom duration was 15 (SD 2.9) years. A total of 36 (40%) patients of working age were not working due to AS. The factors that associated with work disability, after completing logistic regression models, were older age (odds ratio [OR] = 1.8, 95%, confidence interval [CI] = 1.04-1.17), longer disease duration (OR = 1.60, 95% CI = 1.12-2.8), increasing diagnostic delay (OR = 2.1, 95% CI = 1.0-3.4), lower educational level (OR = 3.5, 95% CI = 1.6-6.4), manual profession (OR = 1.80, 95% CI = 1.10-2.6), living in a rural zone (OR = 3.14, 95% CI = 1.98-5.05), peripheral arthritis (OR = 2.04, 95% CI = 1.20-3.43) and psychological symptoms (OR = 2.3, 95% CI = 1.9-4.6).

CONCLUSION

The prevalence of WD among Egyptian patients with AS is considerably high. Clinical and psychosocial factors, in particular, appear to be associated with WD and should therefore be prioritized in clinical practice.

摘要

目的

确定埃及强直性脊柱炎(AS)患者的工作残疾(WD)患病率,并确定与之相关的主要因素。

方法

在 2011 年 7 月至 2012 年 12 月期间,对所有强直性脊柱炎患者进行了一项横断面调查。收集人口统计学数据并进行体格检查。应用多变量模型确定与工作残疾相关的因素。

结果

共有 90 名患者(85 名男性;94.4%)完成了问卷。参与者的平均年龄为 37.8(标准差 9.7)岁,平均病程为 12.1(标准差 8.9)年,平均症状持续时间为 15(标准差 2.9)年。共有 36 名(40%)处于工作年龄的患者因 AS 而无法工作。经过逻辑回归模型后,与工作残疾相关的因素包括年龄较大(优势比 [OR] = 1.8,95%置信区间 [CI] = 1.04-1.17)、病程较长(OR = 1.60,95% CI = 1.12-2.8)、诊断延迟增加(OR = 2.1,95% CI = 1.0-3.4)、教育程度较低(OR = 3.5,95% CI = 1.6-6.4)、从事体力劳动(OR = 1.80,95% CI = 1.10-2.6)、居住在农村地区(OR = 3.14,95% CI = 1.98-5.05)、外周关节炎(OR = 2.04,95% CI = 1.20-3.43)和心理症状(OR = 2.3,95% CI = 1.9-4.6)。

结论

埃及强直性脊柱炎患者的 WD 患病率相当高。临床和社会心理因素,尤其是与 WD 相关的因素,因此应在临床实践中优先考虑。

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